Micro- and nanotechnologies for intelligent and responsive biomaterial-based medical systems |
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Authors: | Mary Caldorera-Moore |
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Affiliation: | a Department of Biomedical Engineering, University of Texas at Austin, 1 University Station, C0800, Austin, TX 78712-0238, USA b Department of Chemical Engineering, University of Texas at Austin, 1 University Station, C0800, Austin, TX 78712-0238, USA |
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Abstract: | Advances in medical treatments of a wide variety of pathophysiological conditions require the development of better therapeutic agents, as well as a combination of the required therapeutic agents with device-integrated biomaterials that can serve as sensors and carriers. Combination of micro- and nano-fabricated systems with intelligent biomaterials that have the ability to sense and respond is a promising avenue for the development of better diagnostic and therapeutic medical systems. Micro- and nano-electromechanical systems (MEMs and NEMs) are now becoming a family of potentially powerful new technologies for drug delivery, diagnostic tools, and tissue engineering. Improvements in micro- and nano-fabrication technologies have enhanced the ability to create better performing therapeutic systems for numerous pathophysiological applications. More importantly, MEMS- and NEMS-based tissue regeneration scaffolds, biosensors, and drug delivery devices provide new opportunities to mimic the natural intelligence and response of biological systems. |
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Keywords: | Responsive hydrogels Intelligent therapeutics Micro- and nano-electromechanical systems Biosensors Controlled drug delivery Tissue engineering |
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