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运用GC-MS结合PCA技术对川白芷与杭白芷挥发油成分的比较分析
引用本文:李玲,吕磊,张薇,赵靖霞,吕狄亚,娄子洋.运用GC-MS结合PCA技术对川白芷与杭白芷挥发油成分的比较分析[J].药物分析杂志,2011(1).
作者姓名:李玲  吕磊  张薇  赵靖霞  吕狄亚  娄子洋
作者单位:第二军医大学药学院分析测试中心;第二军医大学东方肝胆外科医院药材科;
摘    要:目的:运用GC-MS结合主成分分析(PCA)技术对川白芷与杭白芷挥发油成分进行比较分析。方法:采用水蒸气蒸馏法提取川白芷和杭白芷挥发油,运用气相色谱-质谱联用技术,结合计算机检索对其挥发油进行分离鉴定,并结合PCA技术对结果进行验证。结果:共鉴定出川白芷和杭白芷中122个挥发油成分,其中有57个共有成分,两者所含的挥发油在组分和含量上存在一定的差异,PCA分析亦进一步验证了其异同。结论:川白芷与杭白芷挥发油含有大量共有成分,但在组分和含量上存在一定的差异,本研究为川白芷与杭白芷药材的鉴别及质量控制提供了重要依据。

关 键 词:川白芷  杭白芷  挥发油  气质联用  主成分分析  

GC-MS combined with PCA analysis of the essential oil from two varieties of Radix Angelicae Dahuricae
Abstract:Objective:To analyze the chemical components of the essential oil from two varieties of Radix Angelicae Dahuricae by GC-MS combined with principal components analysis(PCA).Methods:The essential oil was extracted from Radix Angelicae Dahuricae by steam distillation;the chemical components of the essential oi1 were detected by GC-MS;Peaks and their corresponding compounds were identified through database index.The results were validated by PCA.Results:122 chief components from two varieties of Radix Angelicae...
Keywords:Radix Angelicae Dahuricae  essential oil  GC-MS  PCA  
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