| 二元手性选择剂体系在毛细管电泳手性拆分中的应用 |
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| 引用本文： | 杜迎翔,刘康.二元手性选择剂体系在毛细管电泳手性拆分中的应用[J].西北药学杂志,2017(1):112-114. |
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| 作者姓名： | 杜迎翔 刘康 |
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| 作者单位： | 1. 中国药科大学分析化学教研室，南京 210009; 中国药科大学药物质量与安全预警教育部重点实验室，南京 210009; 中国药科大学天然药物活性组分与药效国家重点实验室，南京 210009;2. 中国药科大学分析化学教研室,南京,210009 |
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| 基金项目： | 国家自然科学基金项目(编号81001422) |
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| 摘 要： | 目的综述近年来二元手性选择剂毛细管电泳手性拆分体系的最新研究进展。方法主要从双环糊精体系、基于环糊精与其他手性选择剂组成的二元体系和非环糊精类的二元体系这3个方面进行了归纳。结果各类二元手性选择剂体系均能不同程度地改善分离效果,提高分离度。结论二元手性选择剂手性拆分体系具有显著的优越性和广阔的应用前景。
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| 关 键 词： | 毛细管电泳 二元手性选择剂体系 手性拆分 |
Application of two elements chiral selective agent system in chiral separation of cap-illary electrophoresis |
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| DU Yingxiang,LIU Kang.Application of two elements chiral selective agent system in chiral separation of cap-illary electrophoresis[J].Northwest Pharmaceutical Journal,2017(1):112-114. |
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| Authors: | DU Yingxiang LIU Kang |
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| Abstract: | Objective To provide an overview of the recent developments of chiral separation by capillary electrophoresis using dual selector system .Methods Three types of binary systems including dual cyclodextrinsystem ,the cyclodextrin‐based system with other chiral selector and non‐cyclodextrin binary system were reviewed .Results All types of dual selector systems could improve the separation effect for enantioseparation in different degree .Conclusion Dual selector system has significant advantages and broad application prospects . |
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| Keywords: | capillary electrophoresis(CE) two element chiral selector system chiral separation |
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