不同直径半夏药材的质量差异比较研究

目的:考察不同直径半夏药材的质量差异,为其资源的合理利用提供参考。方法:以来自国内四大药材市场、2家公司的65批商品半夏为样品,采用游标卡尺测定其直径后,用分药筛将其筛分为不同直径范围(0.5 cm≤d≤0.8 cm、0.8 cm0.05)。73批半夏对口药材的直径主要分布在0.6~1.8 cm之间,平均重量占比为95.54%。若以2015年版《中国药典》(一部)规定的直径标准(1~1.5 cm),73批半夏对口药材中仅8批符合要求,合格率为10.96%;若适当扩大直径范围为0.7~1.5 cm,有54批符合要求,合格率为73.97%;当直径范围扩大为0.7~1.6 cm时,有68批符合要求,合格率达93.15%。结论:不同直径的半夏药材之间质量无明显差异。结合各产地半夏的直径分布情况,可将相关标准中规定的直径大小由"1~1.5 cm"扩大为"0.7~1.6 cm",避免资源浪费。

Comparative Study on the Quality Differences of Pinelliae Rhizoma with Different Diameter

OBJECTIVE:To investigate the quality differences of Pinelliae Rhizoma with different diameter,and to provide reference for the rational utilization of its resources. METHODS:A total of 65 batches of commercial Pinelliae Rhizoma from the four major medicinal markets in China and two companies were collected as samples,the diameter of them were measured by vernier caliper,and then them were screened into samples with different diameter ranges(0.5 cm≤d≤0.8 cm,0.8 cm0.05). The diameter distribution of 73 batches of Pinelliae Rhizoma from corresponding areas was mainly between 0.6 cm and 1.8 cm,with an average weight of 95.54%. If the diameter standard(1-1.5 cm) specified in the 2015 edition of Chinese Pharmacopoeia(part Ⅰ) was adopted,only 8 of 73 batches of Pinelliae Rhizoma meet the requirements,and the qualified rate was 10.96%;if the diameter range was properly expanded to 0.7-1.5 cm,54 batches of Pinelliae Rhizoma meet the requirements,with a qualified rate of73.97%;when the diameter range was expanded to 0.7-1.6 cm,68 batches of Pinelliae Rhizoma meet the requirements,with a qualified rate of 93.15%.CONCLUSIONS:There is no significant difference in the quality of Pinelliae Rhizoma with different diameters. Combined with the diameter distribution of Pinellia Rhizoma in different producing areas,the diameter range of 1-1.5 cm specified in relative standard can be expanded to 0.7-1.6 cm,avoiding the waste of resources.