| 高效液相色谱法测定胃康灵胶囊中延胡索乙素的含量 |
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| 引用本文： | 陈立娜,马坤芳.高效液相色谱法测定胃康灵胶囊中延胡索乙素的含量[J].中国药房,2006,17(21):1660-1661. |
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| 作者姓名： | 陈立娜 马坤芳 |
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| 作者单位： | 南京医科大学,南京市,210029 |
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| 摘 要： | 目的:建立以反相高效液相色谱(RP-HPLC)法测定胃康灵胶囊中延胡索乙素含量的方法。方法:色谱柱为Shim-Pack VP-ODS,流动相为甲醇-水-三乙胺溶液(70∶30∶0.5),检测波长为280nm,柱温为25℃,流速为1ml/min。结果:延胡索乙素进样量在0.08μg~0.80μg范围内呈良好的线性关系(r=0.9 999,n=5),平均加样回收率为100.76%(RSD=2.13%,n=6)。结论:本方法简便、快速、可靠,可用于该制剂的质量控制。
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| 关 键 词： | 高效液相色谱法 胃康灵胶囊 延胡索乙素 含量测定 |
| 文章编号： | 1001-0408(2006)21-1660-02 |
| 收稿时间： | 08 17 2006 12:00AM |
| 修稿时间： | 09 10 2006 12:00AM |
Determination of Tetrahydropalmatine in Weikangling Capsules by HPLC |
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| CHEN Lina,MA Kunfang.Determination of Tetrahydropalmatine in Weikangling Capsules by HPLC[J].China Pharmacy,2006,17(21):1660-1661. |
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| Authors: | CHEN Lina MA Kunfang |
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| Institution: | Nanjing Medical University, Nanjing 210029, China |
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| Abstract: | OBJECTIVE: To determine the content of tetrahydropalmatine in weikangling capsules by HPLC.METHODS: The separation was performed on a Shim-Pack VP-ODS column,the mobile phase was composed of methanol-water-triethylamine(70∶ 30∶ 0.5),the detection wavelength was 280nm,the column temperature was 25℃ and the flow rate was 1.0ml/min.RESULTS: The linear relation of tetrahydropalmatine was excellent within the range of 0.08μ g～ 0.80μ g(r=0.9 999,n=5),and the mean recovery was 100.76%(RSD=2.13%,n=6).CONCLUSION: The method is simple,rapid and reliable,and can be used for the quality control of weikangling capsules. |
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| Keywords: | HPLC Weikangling capsules Tetrahydropalmatine Determination of content |
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