| 正交试验优选芪七连胶囊制备工艺 |
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| 引用本文： | 陈壮,岳桂华,黄敏,黄小鸥.正交试验优选芪七连胶囊制备工艺[J].中国药房,2012(31):2911-2912. |
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| 作者姓名： | 陈壮 岳桂华 黄敏 黄小鸥 |
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| 作者单位： | 广西中医学院附属瑞康医院;广西中医学院 |
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| 基金项目： | 广西科学研究与技术开发计划课题(桂科攻0993003A-15);广西壮族自治区中医药管理局中医药科技专项课题(GZYZ1109) |
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| 摘 要： | 目的:优选芪七连胶囊的最佳制备工艺。方法:以干膏率和黄芪甲苷含量为评价指标,以加水量、煎煮时间、煎煮次数、醇沉浓度为考察因素,采用L(934)正交试验优选芪七连胶囊的制备工艺。结果:最佳制备工艺为药材加水煎煮2次,第1次加入10倍量水煎煮2h,第2次加8倍量水煎煮2h,醇沉浓度为65%,醇沉24h。结论:优选出的工艺合理、稳定、可行,可用于制备芪七连胶囊。
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| 关 键 词： | 芪七连胶囊 黄芪甲苷 正交试验 制备工艺 |
Optimization of the Preparation Technology of Qiqilian Capsules by Orthogonal Test |
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| CHEN Zhuang,HUANG Min,HUANG Xiao-ou.Optimization of the Preparation Technology of Qiqilian Capsules by Orthogonal Test[J].China Pharmacy,2012(31):2911-2912. |
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| Authors: | CHEN Zhuang HUANG Min HUANG Xiao-ou |
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| Institution: | (The Affiliated Ruikang Hospital of Guangxi Traditional ChineseMedical College,Nanning 530011,China) YUE Gui-hua(Guangxi Traditional Chinese Medical College,Nanning 530001,China) |
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| Abstract: | OBJECTIVE:To optimize the preparation technology of Qiqilian capsules. METHODS:The preparation technologyof Qiqilian capsules was optimized by L(934) orthogonal test with the yield of extract and the content of astragaloside Ⅳ as indexusing amount of added water,decoction time,decoction times and precipitating concentration of ethanol as factors. RESULTS:The optimum preparation technology was as follows:adding 10-fold water at first time and 8-fold water at second time,decoctingfor 2 hour each time,ethanol precipitating concentration of 65% and precipitating for 24 h. CONCLUSION:The optimum processis reasonable,stable and feasible. It is suitable for the preparation of Qiqilian capsules. |
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| Keywords: | Qiqilian capsules Astragaloside Ⅳ Orthogonal test Preparation technology |
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