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吸入噻托溴铵治疗稳定期慢性阻塞性肺疾病的临床研究
引用本文:李素引,崔朝勃,袁雅冬.吸入噻托溴铵治疗稳定期慢性阻塞性肺疾病的临床研究[J].中国药房,2007,18(29):2288-2290.
作者姓名:李素引  崔朝勃  袁雅冬
作者单位:1. 哈励逊国际和平医院呼吸内科,衡水市,053000
2. 河北医科大学第二医院呼吸内科,石家庄市,050000
摘    要:目的:研究吸入噻托溴铵治疗稳定期慢性阻塞性肺疾病(COPD)的治疗效果。方法:60例稳定期COPD患者随机分成2组,治疗组给予噻托溴铵吸入,对照组给予常规治疗,比较2组治疗前后肺功能、6min步行距离并评价临床症状积分。结果:与对照组比较,治疗组FEV1/FVC以及FEV1占预计值百分比明显增加,6min步行距离、临床症状明显改善(P<0.05或P<0.01)。结论:吸入噻托溴铵可有效改善肺功能并缓解临床症状。

关 键 词:噻托溴铵  慢性阻塞性肺疾病  稳定期
文章编号:1001-0408(2007)29-2288-03
收稿时间:2007-02-01
修稿时间:2007-05-14

Tiotropium Bromide Inhalation for Patients with COPD at Stable Stage:Clinical Observation
LI Suyin,CUI Zhaobo,YUAN Yadong.Tiotropium Bromide Inhalation for Patients with COPD at Stable Stage:Clinical Observation[J].China Pharmacy,2007,18(29):2288-2290.
Authors:LI Suyin  CUI Zhaobo  YUAN Yadong
Institution:1.Dept. of Respiratory Diseases, Harrison International Peace Hospital, Hengshui 053000, China;2.Dept.of Respiratory Diseases, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
Abstract:OBJECTIVE: To observe the clinical efficacy of tiotropium bromide inhalation in the treatment of patients with chronic obstructive pulmonary disease(COPD) at stable stage.METHODS: A total of 60 patients with COPD were randomly assigned to receive tiotropium bromide by inhalation(trial group) or conventional therapy(control group).Indices such as lung function,6 minute walk distance,and score of clinical symptoms in the two groups before and after treatment were compared.RESULTS: In trial group compared with the control group,the FEV1/FVC and the percentage of FEV1 in the predicted value increased significantly,and 6 minute walk distance and clinical symptoms showed better improvement(P<0.05 or P<0.01).CONCLUSION: Tiotropium bromide can effectively improve lung function and clinical symptoms in COPD patients.
Keywords:Tiotropium bromide  Chronic obstructive pulmonary disease  Stable stage
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