我院乳腺癌患者围手术期抗菌药物应用分析

目的:评价乳腺癌改良根治术患者围手术期抗菌药物的应用情况。方法:采用回顾性调查方法,对我院2006~2007年乳腺癌改良根治术出院病历资料进行统计、分析。结果:我院乳腺癌改良根治术患者围手术期抗菌药物预防应用率达100%,存在无指征用药、选用广谱抗菌药物不当、频繁换药、盲目联合用药、初次给药时机不当和用药持续时间过长等问题。结论:我院乳腺癌患者围手术期应用抗菌药物存在不合理性,需规范临床医师的用药行为,加强药品管理部门的监督职责。

Perioperative Utilization of Antibacterial Drugs in Patients Undergoing Modified Radical Mastectomy

OBJECTIVE： To evaluate the perioperative utilization of antibacterial drugs in patients undergoing modified radical mastectomy. METHODS： In this retrospective study, the perioperative utilization of antibacterial drugs in patients who underwent modified radical mastectomy during 2006 and 2006 were analyzed statistically. RESULTS： 100% of the patients received antibacterial drugs preventively. The problems involved in the preventive use of antibacterials manifested as medication without indications, irrational application of broad- spectrum antibacterials, frequent change of drugs, blind drug combination, inappropriate time of initial administration and prolonged drug use etc. CONCLUSION： The perioperative use of antibacterial drugs in patients undergoing modified radical mastectomy in our hospital is far from rational. The Clinicians＇ medication behavior should be standardized and supervision on rational drug use should be strengthened.