| 罂硝软膏的制备及质量控制 |
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| 引用本文： | 张玮,刘佃全,薛金红,刘朋川.罂硝软膏的制备及质量控制[J].中国药房,2005,16(4):273-274. |
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| 作者姓名： | 张玮 刘佃全 薛金红 刘朋川 |
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| 作者单位： | 山东潍坊市人民医院药剂科,潍坊市,261041 |
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| 摘 要： | 目的 :制备罂硝软膏 ,并建立质量控制方法。方法 :以硝酸甘油、盐酸罂粟碱、双氯芬酸钾为主药研制软膏剂 ,用紫外分光光度法及酸碱滴定法分别测定硝酸甘油、盐酸罂粟碱、双氯芬酸钾3组分的含量。结果 :硝酸甘油、盐酸罂粟碱、双氯芬酸钾的平均回收率分别为100 65 %、99 86 %、100 55 %,相对标准差分别为0 4945 %、0 1719 %、0 3205 %(n=3)。结论 :该软膏制备工艺可行 ,质量可控 ,性质稳定。
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| 关 键 词： | 罂硝软膏 制备 质量控制 |
| 文章编号： | 1001-0408(2005)04-0273-02 |
| 修稿时间： | 2004年5月9日 |
Study on the Preparation and Quality Control of Papaverine- nitroglycerin Ointment |
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| ZHANG Wei,LIU Dianquan,XUE Jinhong,LIU Pengchuan.Study on the Preparation and Quality Control of Papaverine- nitroglycerin Ointment[J].China Pharmacy,2005,16(4):273-274. |
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| Authors: | ZHANG Wei LIU Dianquan XUE Jinhong LIU Pengchuan |
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| Abstract: | OBJECTIVE:To prepare papaverine-nitroglycerin ointment and to establish a method for its quality control.METHODS:Nitroglycerin,papaverine hydrochloride and diclofenac potassium were used as basic remedies to prepare ointˉment.The contents of nitroglycerin,papaverine hydrochloride and diclofenac potassium were determined by UV-specˉtrophotometric methods.RESULTS:The average recovery rates of Nitroglycerin,papaverine hydrochloride and diclofenac potassium were100.65%、99.86%、100.55%respectively,and RSD equal to0.4945%、0.1719%、0.3205%respectively(n=3). CONCLUSION:The ointment preparation is feasible in technique,reliable in quality control and stable in quality. |
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| Keywords: | Papaverine-nitroglycerin ointment Preparation Quality control |
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