| 盐酸林可霉素滴眼液的HPLC法测定 |
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| 引用本文： | 李红兵,仲娜.盐酸林可霉素滴眼液的HPLC法测定[J].中国药品标准,2002,3(3):42-43. |
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| 作者姓名： | 李红兵 仲娜 |
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| 作者单位： | 青岛药品检验所,青岛,266071 |
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| 摘 要： | 目的：建立盐酸林可霉素滴眼液的含量测定方法。方法：应用高效液相色谱法，ODS－C18术，流动相为0.05mol/L硼砂溶液（用85％磷酸调pH至5.0）－甲醇－乙腈（60：36：3）。结果：测定了三批样品，平均回收率为99.1%（RSD=1.6％）。结论：方法同微生物检定法无显著差异，快速简便，重现性好。
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| 关 键 词： | 盐酸林可霉素滴眼液 高效液相色谱法 含量测定 |
DETERMINATION OF LINCOMYCIN HYDROCHLORIDE EYE DROPS BY HPLC |
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| Authors: | Li Hongbing and Zhong Na |
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| Institution: | Qing dao Institute for Drug Control |
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| Abstract: | Objective: To establish HPLC method for study of Lincomycin Hydrochloride Eye-drops.Methods:It is analyzed by HPLC on a column of ODS-C18 with 0.01mol/LBorax(85% phosphoric acid to pH5.0)Methol-acetonitrile(60:36:3)as mobile phase.Result:Detected 3 lots of samples,the recovery was 99.1%(RSD=1.6%).Conclusion:The method is rapid,simple,repeatable and reliable,it also has no much difference with the method of microbiology. |
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| Keywords: | Lincomycin Hydrochloride Eye-drops HPLC method |
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