| 溃疡性结肠炎患者C-反应蛋白和P-选择素的检测及意义 |
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| 引用本文： | 杨琳,贾延萍,杨宏.溃疡性结肠炎患者C-反应蛋白和P-选择素的检测及意义[J].中国基层医药,2009,16(3). |
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| 作者姓名： | 杨琳 贾延萍 杨宏 |
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| 作者单位： | 1. 济南市槐荫人民医院内科,山东省济南,250021
2. 山东省邹平县中医院 |
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| 摘 要： | 目的 探讨溃疡性结肠炎(UC)患者外周血C-反应蛋白(CRP)和P-选择素(P-sel)的检测及临床意义.方法 检测53例UC患者及35例健康对照组CRP和P-sel水平,分析两者对临床病情程度的影响.结果 活动组患者CRP和P-sel水平明显高于缓解组和对照组(P＜0.05);重度组和中度组明显高于轻度组(P＜0.05,P＜0.01),重度组CRP水平明显高于中度组(P＜0.05);活动期UC患者CRP与P-sel水平呈正相关(r=0.638,P＜0.01).结论 CRP和P-sel与UC的发病及病情严重程度相关.
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| 关 键 词： | 结肠炎 溃疡性 C反应蛋白质 P-选择素 |
Detection and clinical significance of C reactivn protein and P-selectin in patients with ulcerative colitis |
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| YANG Lin,JIA Yan-ping,YANG Hong.Detection and clinical significance of C reactivn protein and P-selectin in patients with ulcerative colitis[J].Chinese Journal of Primary Medicine and Pharmacy,2009,16(3). |
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| Authors: | YANG Lin JIA Yan-ping YANG Hong |
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| Abstract: | Objective To study the detection and clinical signitlcanee of C reactivn protein(ClIP)and P-seleetin(P-sel)in patients with ulcerative colitis(UC).Methods The levels of peripheral blood ClIP and P-sel in patients with UC(n=53)and normal control group(n=35)were detected and the effects on disease severity were analyzed subsequently.Results The levels of blood CRP and P-sel in active phase group were significantly higher than those in catabasis group and normal controls group(P＜0.05);severe stage and medium stage were signiticandy higher than those in mild stage(P＜0.05,P＜0.01),severe stage was significantly higher than those in medium stage(P＜0.05);the blood level of CRP was positively related to P-sel in active phase group(r=0.638,P＜0.01).Conclusion CRP and P-sel were correlated with invasion and severity of UC. |
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| Keywords: | Cditis ulcerative C reactivn proteins P-selectin |
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