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基于中医证候和传统功效的经典名方清金化痰汤研究概况
引用本文:辛辰,李文军,许浚,李翔宇,王权,张铁军,陈常青.基于中医证候和传统功效的经典名方清金化痰汤研究概况[J].现代药物与临床,2019,42(11):2287-2293.
作者姓名:辛辰  李文军  许浚  李翔宇  王权  张铁军  陈常青
作者单位:天津中医药大学 中药学院, 天津 300193,安徽济人药业有限公司, 安徽 亳州 236800,天津药物研究院 中药现代制剂与质量控制技术国家地方联合工程实验室, 天津 300193;天津药物研究院 天津市中药质量标志物重点实验室, 天津 300193,安徽济人药业有限公司, 安徽 亳州 236800,安徽济人药业有限公司, 安徽 亳州 236800,天津药物研究院 中药现代制剂与质量控制技术国家地方联合工程实验室, 天津 300193;天津药物研究院 天津市中药质量标志物重点实验室, 天津 300193,天津药物研究院 天津市中药质量标志物重点实验室, 天津 300193
基金项目:国家重大新药创制科技专项(2018ZX09721004-006)
摘    要:清金化痰汤是治疗咳嗽属痰热壅肺证具有明显特色与优势的经典名方,在感染性肺系疾病如慢阻肺急性加重期、急性支气管炎、慢性支气管炎急性发作期、肺炎、支气管扩张等中广泛应用。总结该方主治病证及适应症、处方功效、古方现代研究进展和临床应用进展,并以AECOPD为例研究清金化痰汤在感染性肺系病中的应用情况,确认本方传统功效与现代适应症有较好的对应关系,且有严格设计的临床研究和有效性的充分证据,是值得深入研究和开发的经典古方。

关 键 词:经典名方  清金化痰汤  研究进展  临床应用  AECOPD
收稿时间:2019/3/15 0:00:00

A survey of classical herbal formulae Qingjin Huatan Decoction based on TCM syndrome and traditional efficacy
XIN Chen,LI Wenjun,XU Jun,LI Xiangyu,WANG Quan,ZHANNG Tiejun and CHEN Changqing.A survey of classical herbal formulae Qingjin Huatan Decoction based on TCM syndrome and traditional efficacy[J].Drugs & Clinic,2019,42(11):2287-2293.
Authors:XIN Chen  LI Wenjun  XU Jun  LI Xiangyu  WANG Quan  ZHANNG Tiejun and CHEN Changqing
Institution:Tianjin University of Traditional Chinese Medicine, college of Chinese Medicine, Tianjin, 300193, China,Anhui Jiren Pharmaceutical Co., Ltd., Bozhou 236800, China,National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine, Tianjin Institute of Pharmaceutical Research, Tianjin, 300193, China;Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China,Anhui Jiren Pharmaceutical Co., Ltd., Bozhou 236800, China,Anhui Jiren Pharmaceutical Co., Ltd., Bozhou 236800, China,National & Local United Engineering Laboratory of Modern Preparation and Quality Control Technology of Traditional Chinese Medicine, Tianjin Institute of Pharmaceutical Research, Tianjin, 300193, China;Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China and Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China
Abstract:Qingjin Huatan Decoction is a classical herbal formulae with obvious characteristics and advantages in the treatment of cough with phlegm-heat obstructing lung syndrome. It is widely used in infectious pulmonary diseases such as AECOPD, acute bronchitis, acute attack of chronic bronchitis, pneumonia and bronchiectasis. This paper summed up the party primary healing and the recipe of indications, efficacy, the viewpoints of modern research progress and clinical application progress, as a case study of AECOPD study Qingjin Huatan Decoction in the application of the department of infectious lung disease, confirming their traditional and modern efficacy indications have good corresponding relationships, and there is sufficient evidence of rigorously designed clinical research and effectiveness. It is classical herbal formulae worthy of in-depth research and development.
Keywords:classical herbal formulae  Qingjin Huatan Decoction  clinical application  AECOPD
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