绿豆癀对大鼠高脂血症的影响

目的 观察绿豆癀对大鼠高脂血症的影响。方法 将Wistar大鼠随机分为对照组，模型组，绿豆癀高、中、低剂量组和绿豆粉组。采用喂饲高脂饲料方法建立大鼠高脂血症模型，末次喂饲后禁食12 h，测定血清三酰甘油（TG）、低密度脂蛋白–胆固醇（LDL-C）、高密度脂蛋白–胆固醇（HDL-C）的量。结果 绿豆癀高剂量能明显降低血清LDL-C（P＜0.01），而且其效果明显比绿豆粉组好（P＜0.05）；绿豆癀各剂量和绿豆粉均能明显降低血清TG、升高血清HDL-C（P＜0.01、P＜0.05），绿豆癀高、中剂量的效果更佳，与绿豆粉相比有明显差异（P＜0.01）。结论 绿豆癀对大鼠高血脂症具有明显的调节作用。

Effects of Mungbean Huang on hyperlipemia in rats

Objective To study the effects of Mungbean Huang on hyperlipermia in rats. Methods Wistar rats were randomly divided into six groups: normal control, model, high-, mid-, and low-Mungbean Huang, and Mungbean Huang powder groups. The hyperlipemic model of rats was established by high-fat diet. Fasting 12 h after the last administration, the concentration of triglyceride (TG), low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein-cholesterol (HDL-C) in serum was determined. Results High-dose Mungbean Huang could significantly decrease the concentrations of LDL-C (P < 0.01), and functioned better than Mungbean Huang powder (P < 0.05). Both Mungbean Huang and Mungbean Huang powder could significantly decrease the concentration of TG and increase the concentration of HDL-C (P < 0.01, P < 0.05). High- and mid-dose Mungbean Huang functioned better than Mungbean Huang powder (P < 0.01). Conclusion Mungbean Huang could obviously improve hyperlipermia in rats.