额力根古日古木-7治疗酒精性肝病的疗效观察

目的观察额力根古日古木-7治疗酒精性肝病的临床疗效和安全性。方法选取内蒙古民族大学附属医院2011年5月—2013年5月收治的60例酒精性肝病患者,随机分为治疗组(30例)和对照组(30例),两组均行严格戒酒,加强营养等支持治疗;对照组口服护肝片,4片/次,3次/d;治疗组口服蒙药额力根古日古木-7,5 g/次,2次/d。两组均治疗1个月。治疗结束后,比较两组患者的临床疗效和治疗前后患者的症状积分、肝功能指标、肝/脾CT比值变化。结果治疗后治疗组患者总有效率93.33%,对照组为70.00%,两组差异具有统计学意义(P<0.05)。治疗前后两组患者蒙医症候积分、肝功能、肝/脾CT比值均得到明显改善,两组差异有统计学意义(P<0.05)。结论额力根古日古木-7治疗酒精性肝病有很好的疗效,可有效恢复患者的肝功能,治疗过程中的不良反应较少,值得临床应用。

Clinical observation of Eligengurigumu-7 on treatment of alcoholic liver diseases

Objective To observe the efficacy and safety of Eligengurigumu-7 in the treatment of alcoholic liver diseases. Methods A total of 60 patients with alcoholic liver diseases from the Affiliated Hospital of Inner Mongolia University for Nationalities during May, 2011 to May, 2013 were randomly divided into treatment (30 cases) and control (30 cases) groups. All the patients were performed strictly to stop drinking and strengthen nutrition. The patients in the control group were po administered with Hugan Tablet, once four pieces, three times daily. The patients in the treatment group were po administered with Eligengurigumu-7, once 5 g, twice daily. The patients in the two groups were treated for 1 month. The clinical efficacy, symptom score, index of liver function, and liver and spleen CT ratio were observed before and after the treatment. Results The efficiency for the patients in both the treatment and control groups were 93.33% and 70.00% with the significant difference (P < 0.05). After treatment, Mongolian medicine symptom score, liver function, and liver and spleen CT ratio of two groups were improved significantly (P < 0.05). Conclusion Eligengurigumu-7 has an accurate curative effect on alcoholic liver diseases, and can recover liver function effectively with low incidence of adverse drug reactions, which could be used in clinic.