蝉花肾损伤保护作用的药理及临床研究进展

蝉花是寄生在蝉上的一种虫草真菌，也是我国传统名贵中药材。现代研究表明蝉花具有免疫调节、改善肾功能、抗疲劳、抗肿瘤、降血糖等广泛的药理作用，临床上用于治疗慢性肾脏病取得良好的疗效。综述天然蝉花或人工培养蝉花延缓糖尿病肾病、抗肾间质纤维化、抗肾小球硬化、保护残肾等对肾损伤保护作用的药理研究进展，以及对慢性肾功能衰竭和慢性间质性肾炎的临床研究进展，以期为开发具有肾损伤保护作用的新药与大健康产品提供依据。

Pharmacological and clinical research progress of Cicada flower in protecting kidney injury

Cicada flower is a cordycipitoid fungus parasitizing cicada nymphs, and it is also a traditional and precious Chinese medicinal material. Modern research shows that cicada flower has a wide range of pharmacological effects such as immunoregulation, improvement of renal function, anti-fatigue, anti-tumor, hypoglycemic, etc., and has achieved good curative effect in the treatment of chronic kidney disease. This article reviews the progress of pharmacological research on renal injury including the protective effects of natural or artificially cultivated cicada flower on diabetic nephropathy, anti-renal interstitial fibrosis, anti-glomerular sclerosis, protection of residual kidney, etc. At the same time, the clinical research progress of chronic renal failure and chronic interstitial nephritis is also reviewed, with a view to providing a basis for the development of new drugs and large health products with protective effects on kidney injury.