| 红芪中红外光谱指纹图谱与其体外抗氧化活性的谱效相关性 |
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| 引用本文： | 余晓晖,夏鹏飞,李彤,刘峰林.红芪中红外光谱指纹图谱与其体外抗氧化活性的谱效相关性[J].中国现代应用药学,2016,33(8):1016-1020. |
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| 作者姓名： | 余晓晖 夏鹏飞 李彤 刘峰林 |
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| 作者单位： | 甘肃中医药大学，兰州 730000；甘肃省高校中(藏)药化学与质量研究省级重点实验室，兰州 730000,甘肃中医药大学，兰州 730000；甘肃省高校中(藏)药化学与质量研究省级重点实验室，兰州 730000,甘肃中医药大学，兰州 730000,甘肃中医药大学，兰州 730000；甘肃省高校中(藏)药化学与质量研究省级重点实验室，兰州 730000 |
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| 基金项目： | 甘肃省自然科学基金(1308RJZA110) |
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| 摘 要： | 目的 探讨红芪中红外光谱(mid-infrared spectrum，MIR)指纹图谱与抗氧化活性之间的谱效关系。方法 采用傅里叶变换红外光谱(FTIR)采集12个产地红芪药材的MIR指纹图谱，采用DPPH法测定12个产地红芪药材的抗氧化作用，采用Person相关性分析与多元非线性回归分析(逐步后退法)构建两者的谱效关系。结果 红芪煎煮液浓度为80 mg·mL-1时对DPPH的清除率最大；红芪MIR指纹图谱与抗氧化活性之间的谱效关系方程为Y=57.329X1-32.913X3+48.571X9(P<0.05，R=0.936)。结论 红芪MIR指纹图谱X1，X3 ，X9峰强度，即3 378，2 372，864 cm-1处吸收峰所代表的化学基团对其抗氧化活性有显著影响。
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| 关 键 词： | 红芪 中红外光谱指纹图谱 抗氧化 谱效关系 |
| 收稿时间： | 2015/12/16 0:00:00 |
| 修稿时间： | 8/2/2016 12:00:00 AM |
Spectrum-effect Relationship Between Mid-infrared Spectrum Fingerprint of Hedysari Radix and Antioxidant Capacity in Vitro |
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| YU Xiaohui,XIA Pengfei,LI Tong and LIU Fenglin.Spectrum-effect Relationship Between Mid-infrared Spectrum Fingerprint of Hedysari Radix and Antioxidant Capacity in Vitro[J].The Chinese Journal of Modern Applied Pharmacy,2016,33(8):1016-1020. |
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| Authors: | YU Xiaohui XIA Pengfei LI Tong and LIU Fenglin |
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| Institution: | Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China; Key Laboratory of Chemistry and Quality for Traditional Chinese Medicines of the College of Gansu Province, Gansu College of Traditional Chinese Medicine, Lanzhou 730000, China,Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China; Key Laboratory of Chemistry and Quality for Traditional Chinese Medicines of the College of Gansu Province, Gansu College of Traditional Chinese Medicine, Lanzhou 730000, China,Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China and Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China; Key Laboratory of Chemistry and Quality for Traditional Chinese Medicines of the College of Gansu Province, Gansu College of Traditional Chinese Medicine, Lanzhou 730000, China |
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| Abstract: | |
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| Keywords: | Hedysari Radix mid-infrared spectrum fingerprint antioxidant spectrum-effect relationship |
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