| 参芍颗粒对急性心肌缺血的影响 |
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| 引用本文： | 闫素云,闫杏莲,崔占军,于东明,高林.参芍颗粒对急性心肌缺血的影响[J].中国现代应用药学,2004,21(4):274-276. |
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| 作者姓名： | 闫素云 闫杏莲 崔占军 于东明 高林 |
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| 作者单位： | 1. 河南大学医学院,河南,开封,475001
2. 河南大学,第一附属医院,河南,开封,475001 |
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| 摘 要： | 目的观察参芍颗粒对犬急性心肌缺血的影响.方法结扎犬冠状动脉前降支,造成急性心肌缺血模型,观察不同剂量对模型犬心肌缺血不同时间血清乳酸脱氢酶(LDH),磷酸肌酸激酶(CPK)和心肌梗死程度的影响.结果参芍颗粒可明显缩小犬N-BT染色所显示的梗死面积,降低心肌缺血模型犬血清的LDH和CPK.结论参芍颗粒能明显改善急性心肌缺血模型犬的心肌缺血程度,缩小心肌梗死范围,具有保护心肌的作用.
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| 关 键 词： | 参芍颗粒 心肌缺血 心肌梗死 血清乳酸脱氢酶 磷酸肌酸激酶 |
| 文章编号： | 1007-7693(2004)04-0274-03 |
Effect of Shenshao granule on acute myocardial ischemia |
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| YAN Su-yun,YAN Xing-lian,CUI Zhang-jun,YU Dong-ming,GAO Lin.Effect of Shenshao granule on acute myocardial ischemia[J].The Chinese Journal of Modern Applied Pharmacy,2004,21(4):274-276. |
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| Authors: | YAN Su-yun YAN Xing-lian CUI Zhang-jun YU Dong-ming GAO Lin |
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| Abstract: | OBJECTIVE To study the effect of Shenshao granule on myocardial ischemia and myocardial infarction in dogs. METHOD Dog models with acute myocardial ischemia was established by the ligation of coronary arteries. RESULTS Shenshao granule significantly improved acute myocardial ischemia in dogs,obviously reduced the infarction area displayed by N-BT staining,decreased CPK,LDH of serum.CONCLUSION Shenshao granule can singnificantly improve myocardial ischemia, reduce the myocardial infarction area. It possessed protective effect on myocardium. |
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| Keywords: | Shenshao granule myocardial ischemia myocardial infarction LDH CPK |
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