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鲎试验和家兔法测定干扰素和白蛋白中内毒素的比较
引用本文:张奇亚,李枫.鲎试验和家兔法测定干扰素和白蛋白中内毒素的比较[J].中国现代应用药学,1989(6):5-7.
作者姓名:张奇亚  李枫
作者单位:中国科学院武汉病毒所实验生物制药厂,中国科学院武汉病毒所实验生物制药厂
摘    要:本文分别用鲎试验和家兔热原法对16批人白细胞干扰素及5批人血浆白蛋白中的内毒素进行了检测。两种方法检测人白细胞干扰素和人血浆白蛋白的符合率分别为81.75%和80%;阴性符合率为100%。

关 键 词:鲎试验  人白细胞干扰素  人血浆白蛋白  内毒素检测

Between Rabbit Pyrogen Test and Limulus Amebocyte Lysate Test Comparative Studies for Detecting Endotoxin in IFN and Serum Albumin
Zhang Qiya Li Feng.Between Rabbit Pyrogen Test and Limulus Amebocyte Lysate Test Comparative Studies for Detecting Endotoxin in IFN and Serum Albumin[J].The Chinese Journal of Modern Applied Pharmacy,1989(6):5-7.
Authors:Zhang Qiya Li Feng
Institution:Bioproduts Factory Wuhan Virology Institute Academia Sanica
Abstract:The results were reported and comparized on detecting endotoxin in 16 samples of Interferon (IFN)and 5 samples of serum albumin by two methods of Rabbit Pyrogen Test(RPT)and Limulus Amebocyte Lysate Test(LAL).The agreement rates of two detecting results are respectively 81.75% and 80% in the samples of IFN and the samples of serum albumin.Both agreement rates of negative results are 100%.The effect of keeping temperature time on the LAL is investigated, showing that the longer the time is the more the pseudopositive rate is produced.
Keywords:Limulus Amebocyte Lysate  Test  (LAL)  Interferon  (IFN)  Serum  Albumin Endotoxin Detection
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