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Versatile methods for synthesizing organic acid salts of quaternary berberine-type alkaloids as anti-ulcerative colitis agents |
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| Authors: | Zhi-Hui Zhang Jing Li Hai-Jing Zhang An-Jun Deng Zhi-Hong Li |
| Institution: | 1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China;2. Key Laboratory of Structure-Based Drug Design &3. Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China |
| Abstract: | |
| Keywords: | Quaternary berberine-type alkaloid organic acid salts synthesis (±)-8-acetonyldihydroberberine-type intermediate dihydroberberine-type intermediate liposolubility XBP1-activating activity |