罗哌卡因用于腰椎间盘摘除、腰椎管减压术最佳浓度探讨

目的探讨一种镇痛、肌松效果好,不良反应少,适用于腰椎间盘摘除、腰椎管减压术,椎管内麻醉用药的最佳浓度。方法选择腰椎间盘突出、腰椎管狭窄患者60例,ASA Ⅰ～Ⅱ级,随机分成3组,每组20例,均选择硬膜外麻醉。A组:硬膜外用0.4%罗哌卡因;B组:硬膜外用0.5%罗哌卡因;C组:硬膜外用0.75%罗哌卡因。对麻醉效果欠佳者,静脉滴注芬太尼0.05mg。结果A组患者镇痛效果欠佳,应用芬太尼例数较多;B组患者镇痛效果好,肌松效果满意,不良反应少;C组患者镇痛、肌松效果较强,不良反应多。结论B组药物浓度是腰椎间盘摘除、腰椎管减压术最佳浓度。

Optimal concentration of ropivacain for lumbar discectomy or lumbar spinal canal decompression

Objective To investigate the optimal concentration of ropivacain for intraspinal anesthesia in lumbar discectomy or lumbar spinal canal decompression procedure.Methods 60 patients with lumbar disc protrusion or lumbar spinal stenosis were randomly divided into three groups.The ASA classification was Ⅰto Ⅱ.Each group was 20 cases and epidural anesthetized.The concentration of ropivacain in group A,B,and C was 0.4%,0.5%,and 0.75% respectively.0.05 mg fentanyl would been intravenous dripped if the analgesia ef...