| 盐酸氨溴索渗透泵控释片的体外释放度考察 |
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| 引用本文： | 潘卫三,常明,刘宏飞,武玉洁,马静.盐酸氨溴索渗透泵控释片的体外释放度考察[J].中国新药杂志,2003,12(7):543-545. |
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| 作者姓名： | 潘卫三 常明 刘宏飞 武玉洁 马静 |
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| 作者单位： | 1. 沈阳药科大学药学院药剂教研室,沈阳110016
2. 河北省石家庄市以岭药业,石家庄,050091 |
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| 摘 要： | 目的：研究盐酸氨溴索渗透泵控释片的体外释放度。方法：考察渗透泵在不同介质中的释放情况。结果：渗透泵的释药不随释药环境的改变而改变。结论：盐酸氨溴索渗透泵控释片释药稳定，零级释药明显，具备优良控释制剂的特征。
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| 关 键 词： | 盐酸氨溴索 渗透泵控释片 体外释放 |
| 文章编号： | 1003-3734(2003)07-0543-03 |
The in vitro release rate of ambroxol HCl osmotic pump controlled release tablets |
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| PAN Wei-san,CHANG Ming,LIU Hong-fei,WU Yu-jie,MA Jing.The in vitro release rate of ambroxol HCl osmotic pump controlled release tablets[J].Chinese Journal of New Drugs,2003,12(7):543-545. |
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| Authors: | PAN Wei-san CHANG Ming LIU Hong-fei WU Yu-jie MA Jing |
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| Institution: | PAN Wei-san1,CHANG Ming1,LIU Hong-fei1,WU Yu-jie1,MA Jing2 |
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| Abstract: | Objective:To study the in vitro release rate of ambroxol HCl osmotic pump controlled release tablets.Methods:The release rate of ambroxol HCl osmotic pump controlled release tablets in various mediums was observed.Results:Drug release rate of the tablets did not change with the change of medium.Conclusions:The ambroxol HCl osmotic pump controlled release tablets have a stable release curve and conform to zero release order. |
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| Keywords: | ambroxol hydrochloride osmotic pump controlled release tablets release in vitro |
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