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| 马齿苋提取物体外清除自由基活性的研究 | |
| 引用本文： | 杨柳,陈承杰,辛海量,李敏.马齿苋提取物体外清除自由基活性的研究[J].药学服务与研究,2011,11(3):186-188. |
| 作者姓名： | 杨柳 陈承杰 辛海量 李敏 |
| 作者单位： | 1. 第二军医大学海医系军队卫生学教研室,上海,200433;上海市青浦区疾病预防控制中心五大卫生科,上海,201700 2. 第二军医大学海医系军队卫生学教研室,上海,200433 3. 第二军医大学长海医院中医科,上海,200433 |
| 摘 要： | 目的:研究马齿苋全草提取物体外的抗氧化活性。方法:选取1,1-二苯基-2-三硝基苯肼(1,1-diphenyl-2-picryl-hydrazine,DPPH)自由基、羟基自由基、超氧阴离子自由基,以及还原能力体系对马齿苋提取物进行抗氧化活性测定。与阳性对照药没食子酸和维生素C作比较。结果:马齿苋提取物清除DPPH自由基、羟基自由基和超氧阴离子自由基的能力在低浓度时弱于阳性对照药没食子酸和维生素C,但随着浓度的增加,其清除活性均明显优于阳性对照药。在0~200μg/ml浓度范围内,马齿苋提取物的还原能力弱于2,6-二叔丁基对甲酚。结论:马齿苋提取物具有较好的清除自由基能力,但还原能力相对较弱。马齿苋可能是有效的外源性天然有机抗氧化剂。 |
| 关 键 词： | 马齿苋 抗氧化剂 自由基 还原剂 |
Study on in vitro scavenging free radical activity of extract from Portulaca oleracea L. |
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| YANG Liu,CHEN ChengJie,XIN HaiLiang,LI Min.Study on in vitro scavenging free radical activity of extract from Portulaca oleracea L.[J].Pharmaceutical Care and Research,2011,11(3):186-188. | |
| Authors: | YANG Liu CHEN ChengJie XIN HaiLiang LI Min |
| Institution: | YANG Liu1,2,CHEN ChengJie1,XIN HaiLiang3,LI Min1(1.Department of Military Hygiene,Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433,China,2.Department of Wuda Health,Centre of Preventing and Controlling Diseases of Shanghai Qingpu District,Shanghai 201700,3.Department of Traditional Chinese Medicine,Changhai Hospital,China) |
| Abstract: | Objective:To investigate antioxidation activities in vitro of extract from Portulaca oleracea L..Methods:Antioxidation activity of the extract was determined by cleaning free radicals of 1,1-diphenyl-2-picrylhydrazine(DPPH),hydroxyl,superoxide negative ion and reducing power assay.Results: The power of the extract at low concentrations for scavenging free radicals of DPPH,hydroxyl and superoxide negative ion were weaker than that of the positive control drugs gallic acid and vitamin C,but with the concentra... |
| Keywords: | Portulaca oleracea antioxidants free radicals reducing agents |
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