| 缬草镇静催眠的物质基础 |
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| 引用本文： | 黄宝康,郑汉臣,秦路平.缬草镇静催眠的物质基础[J].药学服务与研究,2006,6(3):165-168. |
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| 作者姓名： | 黄宝康 郑汉臣 秦路平 |
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| 作者单位： | 第二军医大学药学院生药学教研室,上海,200433 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 缬草（Valeriana officinalis L．）为败酱科缬草属植物，具有镇静催眠活性，在欧美国家广泛用于治疗轻中度失眠。其镇静催眠的活性成分主要集中在挥发油、缬草素类、黄酮类以及水溶性氨基酸成分等。挥发油的特征性成分有乙酸龙脑酯、缬草烯酸，缬草素类成分主要有缬草三酯、二氢缬草素和乙酰缬草素。缬草素类和挥发油类之间可能存在协同作用。
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| 关 键 词： | 缬草 催眠药和镇静药 油类 挥发 黄酮类 生物碱类 综述 |
| 文章编号： | 1671-2838（2006）03-0165-04 |
| 收稿时间： | 2006-01-19 |
| 修稿时间： | 2006-01-192006-03-30 |
Material basis of the sedative and hypnotic activities of Valeriana of ficinalis |
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| HUANG Bao-Kang,ZHENG Han-Chen,QIN Lu-Ping.Material basis of the sedative and hypnotic activities of Valeriana of ficinalis[J].Pharmaceutical Care and Research,2006,6(3):165-168. |
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| Authors: | HUANG Bao-Kang ZHENG Han-Chen QIN Lu-Ping |
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| Institution: | Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433,China |
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| Abstract: | The roots of Valeriana officinalis(family of valerianaceae) have been widely used for treating mild or mode-rate insomnia in Europe and America for a long time.The active substances include total valepotriates,volatile oils,flavones and water(soluble) amino acids.Valerenic acid and bornyl acetate are the characteristic constituents of the volatile oil of valerian.The total valepotriates mainly include valtrate,didrovaltrate and acevaltrate.The volatile oils and total valepotriates may show(synergistic) action. |
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| Keywords: | Valeriana officinalis hypnotics and sedatives oils volatile flavones alka loids review |
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