| 丁香对幽门螺杆菌的体外抑菌作用 |
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| 引用本文： | 韩艳,王庆伟,张琰,刘新友,覃华,杜小燕.丁香对幽门螺杆菌的体外抑菌作用[J].医药导报,2011,30(3):302-303. |
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| 作者姓名： | 韩艳 王庆伟 张琰 刘新友 覃华 杜小燕 |
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| 作者单位： | 第四军医大学唐都医院药剂科,西安,710038 |
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| 摘 要： | ［摘要］目的考察丁香挥发油及丁香酚体外抑制幽门螺杆菌的活性。方法水蒸气蒸馏法提取丁香挥发油，采用高效液相色谱法测定挥发油丁香酚的含量。以氨苄西林为对照，体外法测定丁香挥发油、丁香提取挥发油后的水提取物及丁香酚对8种幽门螺杆菌菌株的最小抑菌浓度（MIC）。结果氨苄西林对8种幽门螺杆菌菌株的MIC范围为1.25～2.50 μg•mL 1，丁香挥发油的MIC范围为5.00～10.00 μg•mL 1，丁香酚的MIC范围为2.50～5.00 μg•mL 1，丁香提取挥发油后的水提取物无抑菌作用。结论丁香抑制幽门螺杆菌的活性成分是其挥发油中的主要成分丁香酚。
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| 关 键 词： | 丁香挥发油 丁香酚 幽门螺杆菌 最低抑菌浓度 |
Anti-Helicobacter Pylori Action of Eugenol and Essential Oil from Eugenia Caryophyllata in vitro |
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| HAN Yan,WANG Qing-wei,ZHANG Yan,LIU Xin-you,QIN Hua,DU Xiao-yan.Anti-Helicobacter Pylori Action of Eugenol and Essential Oil from Eugenia Caryophyllata in vitro[J].Herald of Medicine,2011,30(3):302-303. |
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| Authors: | HAN Yan WANG Qing-wei ZHANG Yan LIU Xin-you QIN Hua DU Xiao-yan |
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| Institution: | HAN Yan,WANG Qing-wei,ZHANG Yan,LIU Xin-you,QIN Hua,DU Xiao-yan(Department of Pharmacy,the Tangdu Hospital,the Fourth Military Medical University,Xi'an 710038,China) |
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| Abstract: | Objective To study the antibacterial effects of eugenol and essential oil from Eugenia Caryophyllata against helicobacter pylori in vitro. Methods The essential oil was obtained by steam distillation.The concentration of eugenol was determined by HPLC.MIC against helicobacter pylori of eugenol,essential oil from Eugenia Caryophyllata and aqueous extract of Eugenia Caryophyllata except essential oil were determined in vitro with ampicillin as a control drug. Results The range of MIC against 8 helicobacter py... |
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| Keywords: | Essential oil from Eugenia Caryophyllata Eugenol Helicobacter pylori MIC |
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