| 原料药乙酰水杨酸中水杨酸的流动注射光度分析法 |
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| 引用本文： | 高立勤,刘枫.原料药乙酰水杨酸中水杨酸的流动注射光度分析法[J].中国药科大学学报,1995,26(5):273-275. |
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| 作者姓名： | 高立勤 刘枫 |
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| 作者单位： | 中国药科大学药物分析教研室 |
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| 摘 要： | 基于水杨酸在ｐＨ２的盐酸介质中与Ｆｅ＾３＋生成紫色络合物，在５２０ｎｍ处有强吸收，而乙酰水杨酸无干扰的原理，建立了流动注射光度法测定原料药乙酰水杨酸中杂质水杨酸的含量，方法快速、简便。在０．０１￣０．２０ｍｇ／ｍｌ浓度范围内线性关系良好，方法回收率为１０１．５％。
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| 关 键 词： | 乙酰水杨酸 水杨酸 流动注射光度法 |
Determination of Salicylic Acid in Bulk Pharmaceuticals of Acetyl-Salicylic Acid by Flow Injection Spectrophotometry |
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| Gao Liqin,Liu Feng,Wang Lixi,Liu Wenying.Determination of Salicylic Acid in Bulk Pharmaceuticals of Acetyl-Salicylic Acid by Flow Injection Spectrophotometry[J].Journal of China Pharmaceutical University,1995,26(5):273-275. |
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| Authors: | Gao Liqin Liu Feng Wang Lixi Liu Wenying |
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| Abstract: | Salicylic acid reacts with Fe3 in pH 2 hydrochloric acid medium to form a violet complex,showing a strong atherption at 520 nm. A flow injection spectrophotometry for the determination of satlicylic acid in bulk pharmaceutical of acetyl salicylic acid is described based on the above reaction.The method is sensitive and accurate the linear range is from 0.01 to 0.20 mg/ml,and the recovery is 101.5%.Meanwhile,it has a high sampling rate of 90 samples per hour. |
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| Keywords: | Salicylic acid Acetyl salicylic acid Flow injection spectrophotometry |
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