| 生脉液,脉络宁及两药合并静脉滴注对麻醉犬脑循环的影响 |
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| 引用本文： | 陈宁红,季慧芳.生脉液,脉络宁及两药合并静脉滴注对麻醉犬脑循环的影响[J].中国药科大学学报,1997,28(4):43-46. |
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| 作者姓名： | 陈宁红 季慧芳 |
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| 作者单位： | 南京市第三人民医院老年病科，中国药科大学生理学教研室 |
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| 摘 要： | 观察了生脉液、脉络宁及两药合并静脉滴注对麻醉犬脑循环的影响。结果表明，生脉液（０．４ｇ／ｋｇ，ｉｖ）、脉络宁（５．５ｇ／ｋｇ，ｉｖ）及两药合并（生脉液０．４ｇ／ｋｇ＋脉络宁５．５ｇ／ｋｇ，ｉｖ）均能增加麻醉犬脑血流量，降低脑血管阻力，合并用药组效果优于单用组。各给药组均有明显的降低血压、减慢心率的作用，随着血压降低，脑血流量亦很快下降，但降低脑血管阻力的作用维持较久。
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| 关 键 词： | 生脉液 脉络宁 脑血流量 脑血管阻力 血压 |
Effects of Shengmai Injection, Mailuoning Injection and the Mixture of Shengmai Injection and Mailuoning Injection on Cerebral Circulation in Anesthetized Dogs |
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| Chen Ninghong,Ji Huifang,Zhang Luyong,Wu Minshu.Effects of Shengmai Injection, Mailuoning Injection and the Mixture of Shengmai Injection and Mailuoning Injection on Cerebral Circulation in Anesthetized Dogs[J].Journal of China Pharmaceutical University,1997,28(4):43-46. |
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| Authors: | Chen Ninghong Ji Huifang Zhang Luyong Wu Minshu |
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| Institution: | Chen Ninghong,Ji Huifang 1,Zhang Luyong 1,Wu Minshu 1 Department of Gereology,The Third Hospital of Nanjing,Nanjing 210008, 1Department of Physiology,China Pharmaceutical University,Nanjing 210009 |
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| Abstract: | The effects of Shengmai Injection(Sheng), Mailuoning injection(Mai) and the solution mixed with Sheng and Mai(Sheng Mai) on cerebral circulation were investigated in anesthetized dogs using the method of electromagnetic flow meter Sheng(0 4 g/kg, iv), Mai(5 5 g/kg, iv) and Sheng Mai(Sheng 0 4 g/kg Mai 5 5 g/kg, iv) significantly increased cerebral blood flow(CBF) and decreased cerebrovascular resistance(CVR) The effects of Sheng Mai group were better than those of individuals The three groups resulted in obvious reduction of blood pressure(BP) and heart rate, with the reduction of BP, CBF decreased, while the reducing effect of CVR lasting longer |
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| Keywords: | Shengmai injectio Mailuoning injectio Cerebral blood flow Cerebrovascular resistance Blood pressure |
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