| 茵栀黄注射液保肝作用的实验研究 |
| |
| 引用本文： | 郭青龙,郭殿武,陈真.茵栀黄注射液保肝作用的实验研究[J].中国药科大学学报,2001,32(6):40-43. |
| |
| 作者姓名： | 郭青龙 郭殿武 陈真 |
| |
| 作者单位： | 1. 中国药科大学生理学教研室,南京,210009
2. 杭州民生药业集团有限公司,杭州,310011 |
| |
| 摘 要： | 目的：研究茵栀黄（Yinzhihuang,YZH）对D－氨基半乳糖（D－Gal）、CCl4所致小鼠急性、大鼠慢性肝损伤模型保肝作用及对小鼠网状内皮系统吞噬功能的影响。方法：以酶的活性、羟脯氨酸含量、郭清指数k和吞噬指数α为指标，结合肝病理组织学检查，观察药物的保肝作用。结果：YZH对小鼠急性、大鼠慢性肝损伤模型均有显著的治疗作用，并能显著提高小鼠郭清指数k和吞噬指数K和吞噬指数α。结论：YZH具有显著保肝作用。
|
| 关 键 词： | 茵栀黄 谷丙转氨酶 谷草转氨酶 肝脏保护 中药 动物实验 |
| 文章编号： | 1000-5048(2001)06-0440-04 |
| 修稿时间： | 2001年9月15日 |
Experimental Research of YZH on the Hepatic Protection |
| |
| GUO Qing-Long,GUO Dian-Wu,CHENG Zhen.Experimental Research of YZH on the Hepatic Protection[J].Journal of China Pharmaceutical University,2001,32(6):40-43. |
| |
| Authors: | GUO Qing-Long GUO Dian-Wu CHENG Zhen |
| |
| Institution: | GUO Qing-Long,GUO Dian-Wu 1,CHENG Zhen Department of Physiology,China Pharmaceutical University,Nanjing 210009, 1Hangzhou Minsheng Pharmaceutical Group Co. Ltd. 310011,China |
| |
| Abstract: | AIM The purpose is to study the hepatic protection of YZH on the models of mice acute damage and rat chronic hepatic injury, and the effect of the phagocytic function of reticuloendothelial system. METHODS The method was conducted by observing the activity of enzymes, the hydroxyproline contain, the clearance index k, phagocytic index and the histopathological lesions of the tissues to study the hepatic protection of YZH. RESULTS YZH has significant hepatic protection on the model of mice acute damage and rat chronic hepatic injury, and is able to improve the phagocytic function of reticuloendothelial system (P<0.01). CONCLUSION YZH has significant hepatic protection. |
| |
| Keywords: | YZH ALT AST Hepatic protection |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国药科大学学报》浏览原始摘要信息 |
| 点击此处可从《中国药科大学学报》下载免费的PDF全文 |
