| 托盘根提取物对不同细胞的影响 |
| |
| 引用本文： | 杜钢军,林海红,许启泰.托盘根提取物对不同细胞的影响[J].中国药科大学学报,2001,32(6):68-70. |
| |
| 作者姓名： | 杜钢军 林海红 许启泰 |
| |
| 作者单位： | 河南大学药学院,开封,475001 |
| |
| 摘 要： | 牛迭肚为蔷薇科悬钩子属植物 ,东北山区广有分布 ,其根药用治疗肝炎、风湿性关节炎、痛风等 1] ,经沈阳药科大学中药研究室鉴定命名为托盘根 ,并用 75 %乙醇回流提取醇提取物 (收率 8%) ,即托盘根提取物 (ethyl alcohol extract from rootsRubuscrataegifolius Bunge,RCE)。十多年来对其的初步研究证明有抗炎、抗氧化及增强免疫作用 2 ,3 ] 。本文就 RCE对不同细胞的影响进行了研究。1 实验材料1 .1 动物昆明种小鼠 ,1 8～ 2 2 g;老龄小鼠 (1 8月龄以上 ) ,雄雌兼用 ,沈阳药科大学动物室提供 ,合格证号 :5 1 7号。1 .2 瘤株S1 80 ,…
|
| 关 键 词： | 肿瘤细胞 淋巴细胞 托盘根提取物 植物药 中药 动物实验 |
| 文章编号： | 1000-5048(2001)06-0468-03 |
| 修稿时间： | 2001年1月5日 |
Effect of Ethanol Extract of Roots of Rubus crataegifolius on Tumor Cells |
| |
| DU Gang-Jun,LIN Hai-Hong,XU Qi-Tai=Pharmaceutical College of Henan University,Kaifeng ==.Effect of Ethanol Extract of Roots of Rubus crataegifolius on Tumor Cells[J].Journal of China Pharmaceutical University,2001,32(6):68-70. |
| |
| Authors: | DU Gang-Jun LIN Hai-Hong XU Qi-Tai=Pharmaceutical College of Henan University Kaifeng == |
| |
| Institution: | DU Gang-Jun,LIN Hai-Hong,XU Qi-Tai=Pharmaceutical College of Henan University,Kaifeng 475001== |
| |
| Abstract: | AIM The purpose is to observe effect of extract from roots of %Rubus crataegifolius%(RCE) on growth of tumor cells and lymphocyte. METHODS Influences of RCE on ultrastructure were observed in tumor cells under the transmit electronic microscope and the influences on growth of different cells were also detected by MTT cyto-dyed. RESULTS RCE could induce tumor cells apoptosis and make mucleiu small, cytoplasm increase, membrane lytic and absorbance of MTT decline, but it could increase absorbance of MTT in lymphocyte. CONCLUSION RCE could inhibit growth of tumor and enhance lymphocyte tranformation.= |
| |
| Keywords: | Tumor cells Lymphocyte Extract of roots of %Rubus crataegifolius |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国药科大学学报》浏览原始摘要信息 |
| 点击此处可从《中国药科大学学报》下载免费的PDF全文 |
|
