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围手术期肠内营养支持对胃肠道恶性肿瘤患者的疗效评估
引用本文:徐海帆,谭风波.围手术期肠内营养支持对胃肠道恶性肿瘤患者的疗效评估[J].海南医学,2011,22(11):14-17.
作者姓名:徐海帆  谭风波
作者单位:南华大学附属第一医院肿瘤外科,湖南,衡阳,421001
摘    要:目的 探讨围手术期肠内营养对胃肠道恶性肿瘤患者的可行性及疗效.方法 选择100例胃肠道恶性肿瘤患者,随机分为两组:实验组50例(肠内营养)和对照组50例(肠外营养),在术前5 d、1 d和术后1 d、7d测量两组患者体重(B、W)、体重指数(BMI)、三头肌皮褶厚度(TSF)、上臂肌围(AMC),并抽取静脉血检测血清白...

关 键 词:胃肠道恶性肿瘤  围手术期  肠内营养  肠外营养

Efficacy evaluation of perioperative enteral nutrition on patients with gi neoplasm malignant
XU Hai-fan,TAN Feng-bo.Efficacy evaluation of perioperative enteral nutrition on patients with gi neoplasm malignant[J].Hainan Medical Journal,2011,22(11):14-17.
Authors:XU Hai-fan  TAN Feng-bo
Institution:,First Affiliated Hospital of Nanhua University,Hengyang 421001,Hunan,CHINA
Abstract:Objective To evaluate the feasibility and curative effects of perioperative enteral nutrition on the patients with gi neoplasm malignant.Methods The patients with gi neoplasm malignant(n=100) were randomly divided into two groups:experimental(enteral nutrition,n = 50) and control(Parenteral nutrition,n=50) groups,then bodyweight(BW),body mass index(BMI),triceps skinfold thickness(TSF),arm muscle circumference(AMC) and venous blood samples were collected to examine the albumin(ALB),Prealbumin(PA),transferrin(TF),NK cell,CD3,CD4,CD8,immunoglobulin IgG,IgA,IgM at the fifth and first day pre-operationally,and first and seventh day post-operatively.Results There were no significant differences between BW,BMI,TSF,AMC on pre-operationally and those on seventh day post-operatively in two groups,and no significant effect of group.There were significant increases in PA and TF,and significant group effect,but the ALB did not increase significantly.There were significant increases in NK cell,CD3,CD4,IgA and IgM of experimental group,whereas,the CD8 and IgG of experimental group and the NK cell,CD3,CD4,CD8,IgG,IgA,IgM of control group did not change significantly.the NK cell,CD3,CD4,IgG,IgA,IgM in the experimental group were significantly higher than those in control group on seventh day post-operatively.Conclusion The application of enteral nutrition in perioperative period can do better in preventing malnutritional status,enhancing the immunological function,decreasing surgical risk and postoperative complications.
Keywords:Gi neoplasm malignant  Perioperative period  Enteral nutrition  Parenteral nutrition
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