维生素D与2型糖尿病患者颈动脉粥样硬化关系的研究进展 |
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引用本文: | 马玲.维生素D与2型糖尿病患者颈动脉粥样硬化关系的研究进展[J].海南医学,2016(3):431-433. |
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作者姓名: | 马玲 |
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作者单位: | 新疆医科大学研究生院,新疆 乌鲁木齐,830054 |
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基金项目: | 国家自然科学基金(81160116) |
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摘 要: | 长期的糖尿病病程可引起血管、心脏、肾脏、神经系统等组织的慢性并发症.维生素D是经典的钙磷调节剂,具有多种生物学效应,包括对胰岛B细胞的保护作用、缓解炎性反应、减少动脉内皮损伤等.近年来愈来愈多的临床及动物模型试验表明,维生素D是2型糖尿病心血管疾病的一个新的危险因素,目前已发表文献对此仍存有分歧,本文就此相关机制及临床研究做一综述.
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关 键 词: | 2型糖尿病 颈动脉粥样硬化 维生素D |
Advance on the relationship between Vitamin D and carotid atherosclerosis in patients with type 2 diabetes mellitus |
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Abstract: | Diabetes of long duration can cause chronic complications of blood vessels, heart, kidneys, nervous system and other tissues. Vitamin D is a classic regulator of calcium and phosphorus, which has a variety of biological ef-fects, including protecting pancreatic B cells, relieving inflammation, reducing arterial endothelial injury. In recent years, an increasing number of clinical and animal model experiments show that Vitamin D is a new risk factor for cardiovascu-lar disease in patients with type 2 diabetes mellitus, but researches published still exist differences for this point. This arti-cle reviews the current related researches and studies. |
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Keywords: | Type 2 diabetes mellitus Carotid atherosclerosis Vitamin D |
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