CK-MB在儿童支气管肺炎辅助检查中的临床意义

目的 探讨血清磷酸肌酸同工酶(CK-MB)检测在儿童轻症支气管肺炎辅助检查中的临床意义,以期指导临床诊治.方法 收集2015年1~8月85例本院收治的轻症支气管肺炎患儿,分为学龄期组(7~14岁) 6例、学龄前期组(4~6岁) 22例和婴幼儿期组(0~3岁) 57例,入院时常规检测患儿CK-MB的数值,分析其在不同年龄组中的变化情况.结果 85例住院患儿中男性49例,女性36例,婴幼儿组11例患儿CK-MB升高(19%),学龄前期患儿组1例升高(5%),学龄期组患儿无一例CK-MB升高.男性患儿CK-MB数值为(2.40±1.76) ng/ml,女性患儿为(2.93±1.96) ng/ml,两者比较差异无统计学意义(P>0.05).婴幼儿组患儿CK-MB为(3.23±1.84) ng/ml,学龄前期组为(1.58±1.27) ng/ml,学龄期组为(0.75±0.57) ng/ml,婴幼儿组支气管肺炎患儿血液CK-MB数值较学龄前期和学龄期患儿显著升高,差异均有统计学意义(P<0.05).结论 CK-MB是目前临床判断患儿心肌受损的经典检测指标,婴幼儿支气管肺炎轻症合并心肌受损的发生概率相对较高,血清CK-MB的检测应作为婴幼儿支气管肺炎的常规检查,可以使患儿得到更好的诊治.对于学龄前期和学龄期轻症支气管肺炎患儿,血清CK-MB可不作为临床常规的辅助检查.

Clinical value of serum CK-MB in the auxiliary examination of children with bronchial pneumonia

Objective To explore the clinical value of serum creatine kinase isoenzyme MB (CK-MB) in auxil-iary examination of children with bronchial pneumonia. Methods A total of 85 patients with bronchial pneumonia ad-mitted to hospital from January 2015 to August 2015 were randomly enrolled, which were divided into infant and tod-dler's age group (0~3 years, 57 cases), preschool age group (4~6 years, 22 cases), and school age group (7~14 years, 6 cases). The levels of patients' serum CK-MB on admission were measured, and the changes were evaluated in different groups. Results Among the 85 patients, there were 49 males and 36 females. The serum CK-MB levels were increased in 11 patients in the infant and toddler's age group, 1 patient in the preschool age group, and no patient in the school age group. The level of serum CK-MB was (2.40 ± 1.76) ng/ml in male patients and (2.93 ± 1.96) ng/ml in female patients, with no statistically significant difference (P>0.05). The level of serum CK-MB was (3.23±1.84) ng/ml in infant and tod-dler's age group, which were significantly higher than (1.58 ± 1.27) ng/ml in preschool age group and (0.75 ± 0.57) ng/ml in school age group (P<0.05). Conclusion Serum CK-MB is a classic detection index for clinical diagnosis of myocar-dial damage. The incidence of myocardial damage in children with bronchial pneumonia is relatively high in infant and toddler's age group. The serum CK-MB test should be used as routine examination for infants and toddlers with bronchi-al pneumonia to get better treatment. Meanwhile, the test may not be used as a clinical routine auxiliary examination for preschool and school age children with bronchial pneumonia.