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壁面弹性对分叉颈动脉个体化病例血流动力学影响的数值模拟
引用本文:邱晓宁,费智敏,张珏,王炜哲,曹兆敏.壁面弹性对分叉颈动脉个体化病例血流动力学影响的数值模拟[J].上海交通大学学报(医学版),2011,31(11):1554-1559.
作者姓名:邱晓宁  费智敏  张珏  王炜哲  曹兆敏
作者单位:1. 上海交通大学机械系统与振动国家重点实验室,上海,200240
2. 上海中医药大学附属曙光医院神经外科,上海,203204
3. 上海交通大学医学院附属仁济医院神经外科,上海,200127
基金项目:中华医学会临床医学科研专项基金(09010200175); 国家自然科学基金(50906049); 机械系统与振动国家重点实验室课题资助项目(MSV201115)~~
摘    要:目的基于颈动脉的壁面弹性变形对血流动力学变化的重要影响,研究血流动力学与分叉颈动脉粥样硬化之间的关系。方法采用Mimics软件对CT医学影像三维重建,得到1例真实人体颈动脉分叉模型,利用计算流体力学对该模型分别以刚性壁面和弹性壁面进行三维流动数值模拟计算。通过壁面位移、壁面应力、时间平均壁面剪应力(TAWSS)、震荡剪切指数(OSI)等血流动力学参数对比分析刚性模型与弹性模型的差异。结果相对刚性模型而言,尽管颈动脉内的速度分布和壁面剪应力分布趋势差异不大,但颈动脉内速度有显著下降、壁面剪应力也有大幅降低。在该例数值计算中,最大流动速度约下降14%,而TAWSS则下降了11.8%。壁面变形导致的血流扰动使得颈动脉内的流动更加复杂。结论弹性壁面对分叉颈动脉的血流动力学具有重要影响,可以更合理地模拟心血管内的流动问题。

关 键 词:分叉颈动脉  动脉粥样硬化  血流动力学  计算流体力学  流固耦合

Numerical simulation of influence of wall elasticity of patient-specific carotid bifurcation on hemodynamics
QIU Xiao-ning,FEI Zhi-min,ZHANG Jue,WANG Wei-zhe,CAO Zhao-min.Numerical simulation of influence of wall elasticity of patient-specific carotid bifurcation on hemodynamics[J].Journal of Shanghai Jiaotong University:Medical Science,2011,31(11):1554-1559.
Authors:QIU Xiao-ning  FEI Zhi-min  ZHANG Jue  WANG Wei-zhe  CAO Zhao-min
Institution:QIU Xiao-ning1,FEI Zhi-min2,ZHANG Jue3,WANG Wei-zhe1,CAO Zhao-min1(1.State Key Laboratory of Mechanical System and Vibration,Shanghai Jiaotong University,Shanghai 200240,China,2.Department of Neurosurgery,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 203204,3.Department of Neurosurgery,Renji Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200127,China)
Abstract:Objective To investigate the relationship between bifurcation carotid atherosclerosis and hemodynamics by analysing the influence of carotid artery elastic wall deformation on hemodynamics.Methods A carotid bifurcation model was developed by Mimics software through three-dimensional reconstruction of CT medical images.Three-dimensional flows of rigid wall model and elastic wall model were numerically simulated through computational fluid dynamics.The differences between rigid and elastic models were analyse...
Keywords:carotid bifurcation  atherosclerosis  hemodynamics  computational fluid dynamics  fluid structure interaction  
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