| 直肠癌组织中EB病毒的原位杂交检测 |
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| 引用本文： | 闫海龙,张建立,胡顺霞,崔建,孙振青.直肠癌组织中EB病毒的原位杂交检测[J].齐鲁医学杂志,2014(3):202-203,206. |
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| 作者姓名： | 闫海龙 张建立 胡顺霞 崔建 孙振青 |
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| 作者单位： | [1]青岛大学附属医院普外科,山东青岛266003 [2]青岛市妇女儿童医院检验科,山东青岛266003 |
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| 摘 要： | 目的探讨EB病毒（EBV）感染与人直肠癌发生的关系。方法采用原位分子杂交技术，对100例人直肠癌组织标本中EBV编码小分子RNA（EBER）进行检测。结果100例直肠癌标本中癌细胞EBER均为阴性，有1例直肠癌组织间质中浸润的淋巴细胞EBER阳性。结论EBV感染与直肠癌的发生无明显相关性。
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| 关 键 词： | 直肠肿瘤 单纯疱疹病毒属 原位杂交 |
DETECTION OF IN SITU HYBRIDIZATION OF EPSTEIN-BARR VIRUS IN RECTAL CANCER |
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| YAN Hailong,ZHANG Jian- li,HU Shunxia,CUI Jian,SUN Zhenqing.DETECTION OF IN SITU HYBRIDIZATION OF EPSTEIN-BARR VIRUS IN RECTAL CANCER[J].Medical Journal of Qilu,2014(3):202-203,206. |
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| Authors: | YAN Hailong ZHANG Jian- li HU Shunxia CUI Jian SUN Zhenqing |
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| Institution: | (Department of General Surgery, The Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, China) |
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| Abstract: | Objective To investigate the relationship between epstein-barr virus （EBV） and rectal cancer. Methods Applying in situ molecular hybridization technique, the small-molecule RNA fragments of EBV in samples of 100 patients with rec- tal cancer were detected. Results EBV was not found in the cancer specimens. One of the cases was found infiltrative lympho- cytes in interstitial tissue. Conclusion EBV infection is not associated with the occurrence of rectal cancer. |
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| Keywords: | rectal neoplasms simplexvirus in situ hybridization |
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