珍稀动物性药材替代策略及其科技创新与产业化进展

野生药用动物驯化养殖和珍稀濒危动物药的替代资源研究与开发是国家重大任务, 回顾和分析了我国动物药资源及替代研究的历史与现状, 提出了野生药用动物驯化养殖替代策略、基于中医药理论的药性与功效相似药材替代策略、基于动物种类亲缘学的同种属或近缘药材替代策略、基于药效成分组合的合成替代策略、基于生物学技术的合成替代策略等珍稀动物药替代方法, 以期为珍稀动物药替代品的研究提供借鉴与指引, 实现动物药资源的可持续发展与利用。 

Alternative Strategies for Precious Animal Derived Chinese Medicines Materials and Progress in Technological Innovation and Industrialization

The domestication of wild medicinal animals and the research of alternative resources for rare and endangered animal medicines are major national tasks and the fundamental ways to balance the contradiction between animal protection and health needs. This paper summarizes the history and current situation of animal medicine resources and substitution research, and proposes alternative methods for the substitution of precious animal medicines, such as domestication and breeding of wild medicinal animals, substitution of medicinal herbs with similar medicinal properties and efficacy based on the theory of Chinese medicine, substitution of herbs of the same genus or close relatives based on the kinship of animal species, synthetic substitution based on the combination of medicinal components, and synthetic substitution based on biological technology. The aim is to provide reference and guidance for the research on the substitution of precious animal medicines and to achieve the sustainable development and utilization of animal medicine resources.