表皮生长因子(EGF)影响舌苔形成的分子机制 |
| |
作者姓名: | 周坤福 詹瑧 侯亮 |
| |
作者单位: | 南京中医药大学基础医学院,江苏,南京,210029 |
| |
基金项目: | 国家自然科学基金资助项目 (3 0 0 70 910 ) |
| |
摘 要: | 目的 通过皮下注射EGF,观察小鼠舌上皮细胞生长和EGF-R的表达,研究EGF影响舌苔形成的分子机制,方法 HE染色,EGF-RSABC免疫组化染色和图像分析数据处理系统(CMIAS-98A多功能图像分析仪)进行分析。结果 EGF促进小鼠舌上皮增厚,基底层细胞数增多,EGF-R表达增多。结论 EGF可以通过EGF-R机制影响舌苔形成。
|
关 键 词: | 表皮生长因子 舌苔 免疫组化 图像分析 分子机制 |
文章编号: | 1000-5005(2002)05-0283-03 |
修稿时间: | 2002年3月17日 |
Molecular Mechanism of Epidermis Growth Factor (EGF) in Affecting Formation of Tongue Coating |
| |
Authors: | ZHOU Kun fu ZHAN Zhen HOU Liang |
| |
Abstract: | OBJECTIVE EGF was injected to observe the growth of tongue epithelium of mice and EGF-R expression, so as to investigate into the molecular mechanism of EGF in affecting the formation of tongue coating. METHOD HE pigmentation, EGF-R SABC immunology and histochemistry pigmentation and graph analysis and data processing system (CMIAS-98A multifunctional graph analyzer) were used in the analysis.RESULT EGF could promote the thickening of the mice tongue epithelium and increase the number of basal cells and EGF-R expression.CONCLUSION EGF can affect the formation of tongue coating through EGF-R. |
| |
Keywords: | epidermis growth factor tongue coating immunology and histochemistry graph analysis molecular mechanism |
本文献已被 CNKI 维普 万方数据 等数据库收录! |