犀角及羚羊角替代资源的寻找与评价研究(Ⅱ) |
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作者姓名: | 王斐 段金廒 钱大玮 李友宾 |
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作者单位: | 1. 江苏省苏州市中医医院药剂科,江苏,苏州,215003 2. 南京中医药大学,江苏,南京,210046 3. 江苏省中医药研究院,江苏,南京,210028 |
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基金项目: | 西部开发科技行动项目
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国家中医药管理局科研项目 |
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摘 要: | 目的 犀角及羚羊角替代资源的寻找与评价.方法 运用高效液相色谱法测定对八种角中牛磺酸及胆固醇进行分析,运用分光光度法对其中的氨基己糖及游离蛋白进行了分析.结果 对角类药材中牛磺酸、胆固醇、氨基己糖、蛋白质进行了分析.结论 结果准确可靠、快速、灵敏、重现性好.研究结果提示,牛磺酸可能是角类药材的活性物质之一;不同种类角中的小分子成分组成相似,但含量相差较大.
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关 键 词: | 角类 牛磺酸 胆固醇 氨基己糖 蛋白质 犀角 羚羊面 替代资源 犀角 羚羊角 替代资源 评价研究 Evaluation Substitutes 含量 相似 组成 成分 分子 种类 活性物质 快速 蛋白质 角类药材 结果 游离蛋白 氨基己糖 分光光度法 |
文章编号: | 1000-5005(2007)01-0036-04 |
收稿时间: | 2006-08-03 |
修稿时间: | 2006-08-29 |
Searching for Substitutes for Cornu Rhinoceri Asiatici and Cornu Saigae Tataricae and Evaluation (Ⅱ) |
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Authors: | WANG Fei DUAN Jinao QIAN Da-wei LI You-bin |
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Institution: | 1 Pharmaceutical Department of Suzhou Municipal TCM Hospital, Suzhou, Jiangsu, 215003, China; 2 Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, 210029, China; 3 TCM Research Institute of Jiangsu Province, Nanjing, Jiangsu, 210028, China |
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Abstract: | OBJECTIVE To search for the substitutes for Comu Rhinoceri Asiatici and Comu Saigae Tataricae and make evaluations. METHOD HPLC method was used to analyze aminoethyisulfonic acid and cholesterol, and spectrophotometry was used to analyze aminohexose and free protein in eight kinds of homs. RESULT Analyses were made on aminoethyisulfonic acid, cholesterol, spectrophotometry, aminohexose and protein. CONCLUSION The method was accurate, speedy and sensitive, with good reproductivity. The result shows that aminoethyisulfonic acid might be one of the active substances in medicated horns, with similar constituents in the micromoleculs of different kinds of horns but different contents. |
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Keywords: | horns aminoethyisulfonic acid cholesterol aminohexose protein Comu Rhinoceri Asiatici Comu Saigae Tataricae substitutes |
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