心外膜脂肪平均厚度与冠心病的相关性

目的探讨心外膜脂肪平均厚度与冠心病的关系。方法选取228例行冠脉造影的患者，并根据检查结果分为冠心病组和非冠心病组，各114例。采用CT技术测量心外膜脂肪厚度，并比较两组患者年龄、性别、体重指数、收缩压、舒张压、空腹血糖、总胆固醇、LDL—C、HDL—C及心外膜脂肪平均厚度。将上述有统计学差异的因素行binary Logistic回归分析，检验两组患者心外膜脂肪平均厚度是否仍有差异。结果（1）冠心病组心外膜脂肪平均厚度为（6．27±285）mm，非冠心病组为（4．24±259）mm，冠心病组患者心外膜脂肪厚度明显高于非冠心病组（P〈0．05）。（2）Logistic回归分析示，在均衡其它因素后，冠心病组与非冠心病组间心外膜脂肪平均厚度的差异依然存在统计学意义（P〈0.05）.结论心外膜脂肪平均厚度与冠心病相关，可被视为冠心病的一个危险因素。

Correlation of epicardial adipose tissue thickness with coronary heart disease

Objective TO evaluate the relationship between mean thickness of epicardial adipose tissue （EAT） and coronary heart disease （CHD）. Methods Two hundred and twenty eight subjects underwent coronary angiography, according the results they were divided into two groups： CHD and non-CHD with 114 in each. EAT thickness was assessed by CT. The data （include age, sex, body mass index, systolic pressure, diastolic pressure, fasting blood glucose, TC, HDL-c, LDL-c, TG and EAT mean thickness） were compared between two groups and analyzed with binary logistic regression. Results The group has coronary artery disease, mean thickness EAT of CHD group was higher than that of non-CHD group （6.27 ± 2.85mm vs 4.24 ±2.59mm, P〈0.05）. After the baseline was balanced, logistic regression analysis showed there was still statistical significance between two groups（ P〈0.05 ）. Conclusion Mean thickness of EAT was associated with coronary heart disease and can be used as a valuable predictor for coronary heart disease.