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恶性肿瘤并发血栓性疾病临床分析
引用本文:张丽,王燕,曹建存,马力.恶性肿瘤并发血栓性疾病临床分析[J].天津医科大学学报,2011,17(1):54-56.
作者姓名:张丽  王燕  曹建存  马力
作者单位:1. 天津医科大学研究生院,天津,300070
2. 天津医科大学总医院肿瘤科,天津,300052
摘    要:目的:了解恶性肿瘤合并血栓性疾病的临床和实验室特点。方法:对33例恶性肿瘤合并血栓性疾病患者的临床特点及化疗前血常规、凝血功能等进行回顾性分析。结果:血栓组病例占同期发病的6.1%,且以深部静脉血栓形成(VTE)为主。血栓性疾病可能是恶性肿瘤的首发表现,以血栓事件起病的恶性肿瘤中44.4%已发生远处转移。恶性肿瘤血栓组1年及1年半生存时间较非血栓组短(P〈0.05)。血栓组和非血栓组相比,抗肿瘤治疗前血小板、白细胞、凝血酶原时间(PT)及D-D(DD)水平存在显著差异(P〈0.05)。结论:伴有血小板、白细胞和DD升高的恶性肿瘤患者,更易发生血栓事件,预后差,应早期发现并干预治疗,延长患者生存时间,提高生活质量。

关 键 词:恶性肿瘤  血栓性疾病  高凝状态  抗凝

Clinical analysis of malignant tumor with thrombosis
ZHANG Li,WANG Yan,CAO Jian-cun,MA Li.Clinical analysis of malignant tumor with thrombosis[J].Journal of Tianjin Medical University,2011,17(1):54-56.
Authors:ZHANG Li  WANG Yan  CAO Jian-cun  MA Li
Institution:ZHANG Li1,WANG Yan2,CAO Jian-cun1,MA Li2(1.Graduate School,Tianjin Medical University,Tianjin 300070,China,2.Department of Oncology,General Hospital,Tianjin 300052,China)
Abstract:Objective: To understand the clinical and laboratory features of malignant tumor with thrombosis.Methods: Clinical features,blood routine,blood clotting function of 33 in-patients who were diagnosed malignant tumor with thrombosis were retrospectively reviewed.Results: Among these 33 patients,occupied 6.1% of the total,VTE was the most popular one.Thrombosis could be first clinical feature of malignant tumor,44.4% of which had metastasis.The survival time of one year and one year and a half in malignant tum...
Keywords:Malignant tumor  Thrombosis  Hypercoagulabale state  Anticoagulation  
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