| 家兔急性高眼压后视网膜G－6－Pase，磷酸化酶及ACP组织化学研究 |
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| 引用本文： | 高建鲁,孙为荣,杨湘娟,杨文意,康菊,赵洁.家兔急性高眼压后视网膜G－6－Pase，磷酸化酶及ACP组织化学研究[J].青岛大学医学院学报,1994(4). |
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| 作者姓名： | 高建鲁 孙为荣 杨湘娟 杨文意 康菊 赵洁 |
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| 作者单位： | 山东省聊城地区人民医院 |
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| 摘 要： | 采用光镜酶组织化学和电镜细胞化学方法，对家兔急性高眼压后视网膜内与糖代谢及分解代谢有关的葡萄糖－６－磷酸酶（Ｇ－６－Ｐａｓｅ）、磷酸化酶和酸性磷酸酶（ＡＣＰ）进行了研究。结果显示：高眼压后７～１５ｄ磷酸化酶活性明显下降（Ｐ＜０．０５），ＡＣＰ活性明显增强，色素上皮（ＲＰＥ）溶酶体内容物有释放现象。提示急性高眼压后存在糖原代谢障碍；ＡＣＰ参与了视网膜损伤过程。
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| 关 键 词： | 葡萄糖磷酸酶类，磷酸化酶，酸性磷酸酶类，眼高压，视网膜，兔 |
THE HISTOCHEMISTRY INVESTIGATION ON G-6-Pase,PHOSPHORYLASE AND ACP IN THE RETINA OF RABBITS AFTER ACUTE OCULAR HYPERTENSION |
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| Gao Jianlu,Sun Weirong,Yang Xiangjuan,et al.THE HISTOCHEMISTRY INVESTIGATION ON G-6-Pase,PHOSPHORYLASE AND ACP IN THE RETINA OF RABBITS AFTER ACUTE OCULAR HYPERTENSION[J].Acta Academiae Medicinae Qingdao Universitatis,1994(4). |
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| Authors: | Gao Jianlu Sun Weirong Yang Xiangjuan |
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| Institution: | Liaocheng District Hospital of Shandong |
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| Abstract: | The enzymes with relation to metabolism in the retinae of rabbits after acute ocluar hypertension were investigated by means of quantitative histochemistry and electron microscopic histocytochemistry.The result showed that the phosphorylase activity of a hypertensional retina became lower and ACP activity became higher in 7 to 15 days(P<0.05).In addition,the ACP was released from lysosomes of RPE,It can be concluded that there exists a metabolic obstruction of glucogen and that ACP may play an important role in the retinal damage after acute ocular hypertension. |
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| Keywords: | glucose phosphatase phosphorylarse acid phosphatase enzyme retina ocular hypertension |
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