氯诺昔康抑制人工流产术后子宫收缩疼痛的观察

目的:观察氯诺昔康8mg术前静脉注射对静脉麻醉以及人工流产术后子宫收缩疼痛的作用.方法:80例行异丙酚静脉麻醉下人工流产手术的患者随机分为两组:氯诺昔康组术前10min静脉注射氯诺昔康8mg,对照组术前10min静脉注射安慰剂(生理盐水).观察记录两组患者手术中异丙酚的用量、术后疼痛评分以及补救镇痛药的用量.结果:两组患者手术中异丙酚的用量无显著性差异.术后疼痛评分氯诺昔康组显著低于对照组(P＜0.05).补救镇痛药在对照组使用比例更高(P＜0.05).结论:术前静脉注射氯诺昔康并不影响人工流产手术中静脉麻醉药的用量,可明显缓解术后子宫收缩疼痛.

Effects of preoperatively administered lornoxicam on the action of intravenous anesthesia and postoperative pain

Objective:To evaluate the effect of preoperatively intravenous lornoxicam on the action of intravenous anesthesia and postoperative pain.Methods:Eighty patients undergoing induced abortion with propofol were allocated randomly into two groups.The lornoxicam group of 40 patients received 8mg lornoxicam i.v.10 minutes before the start of surgery.The control group of 40 patients received intravenous NaCl 0.9% 10 minutes before the start of surgery.The quantity consumed of propofol,postoperative pain and on-demand pethidine consumption were measured.Results:No significant differences were observed concerning the quatity consumed of propofol.The lornoxicam group showed lower pain scores and required less pethidine than the control group(P<0.05).Conclusion:Preoperative administered lornoxicam relieves postoperative pain after induced abortion,but does not affect the action of the intravenous anesthetic.