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蓝光对痤疮患者的疗效及对糠秕马拉色菌的影响
引用本文:穆艳蕾,杨蓉娅,王文岭,樊昕,徐阳,王聪敏,张洁.蓝光对痤疮患者的疗效及对糠秕马拉色菌的影响[J].第三军医大学学报,2009,31(22):2269-2271.
作者姓名:穆艳蕾  杨蓉娅  王文岭  樊昕  徐阳  王聪敏  张洁
作者单位:北京军区总医院全军皮肤病诊治中心,北京,100125
摘    要:目的 观察波长407~420 nm蓝光对痤疮患者的疗效,对面部皮肤皮脂溢出率及糠秕马拉色菌的影响.方法 对20例痤疮患者蓝光治疗前后行电子显微成像观察,评价靶疹的表皮层及真皮浅层变化;应用Looking bill及Cunliffe改良测定法进行皮脂溢出率测定;应用蓝光对培养的糠秕马拉色菌进行照射,观察照光前后菌落的数量及形态变化.结果 20例痤疮患者蓝光治疗后靶疹明显消退,其表皮层及真皮浅层损伤减轻;皮脂溢出率较治疗前显著减少(P<0.01);在0.5 ml细胞数为5×10~6/ml的糠秕马拉色菌菌液中,菌落数量、直径与光照时间成反比,蓝光光照时间大于3 min 30 s时,平吼内无菌落生长.结论 蓝光对痤疮有很好的治疗效果:能修复深至真皮层的皮肤损伤,抑制皮脂分泌,对糠秕马拉色菌有杀菌作用.

关 键 词:痤疮  蓝光  皮肤性质  皮脂溢出率  糠秕马拉色菌

Effects of blue light therapy on acne and Malassezia furfur
MU Yan-lei,YANG Rong-ya,WANG Wen-ling,FAN Xin,XU Yang,WANG Cong-min,ZHANG Jie.Effects of blue light therapy on acne and Malassezia furfur[J].Acta Academiae Medicinae Militaris Tertiae,2009,31(22):2269-2271.
Authors:MU Yan-lei  YANG Rong-ya  WANG Wen-ling  FAN Xin  XU Yang  WANG Cong-min  ZHANG Jie
Institution:MU Yan-lei,YANG Rong-ya,WANG Wen-ling,FAN Xin,XU Yang,WANG Cong-min,ZHANG Jie (Center of Dermatology,General Hospital of Beijing Military Command,Beijing 100125,China)
Abstract:Objective To investigate the effects of blue light(407 to 420 nm) therapy on acne,facial sebum excretion rate and the growth of Malassezia furfur isolated from acne lesions.Methods Twenty cases of acne patients were treated with the blue light system.Before and after the treatments,electronic microscopy were used to assess the change of the target acne in epidermis and dermis.Looking bill and Cunliffe's technique was used to test the sebum excretion rate(SER).Selected bacterial strains of Malassezia furfur ...
Keywords:acne  blue light  skin property  sebum excretion rate  Malassezia furfur
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