重庆市城区正常人群骨密度状况分析

目的 了解重庆市城区正常人群各部位骨密度随增龄出现的变化规律；探讨骨峰值年龄；分析各部位BMD下降幅度较大的年龄段，以指导临床预防和治疗原发性骨质疏松。方法 选择居住在重庆市10年以上的门诊和查体人群1320人(除外患骨代谢疾病的患者)，采用双能X线骨密度仪测定腰椎前后位(L2-4)、股骨近端(Neck、Ward’s、Troch)骨密度，男女分别按5岁一个年龄段，共14组段进行统计学分析。结果 ①男女各部位骨峰值均出现在25～29岁年龄段。②女性腰椎前后位(L2-4)、Ward’s、Troch区骨密度下降幅度最大的年龄段为45～55岁，股骨近端骨密度下降幅度最大的年龄段为55～59岁。男性峰值年龄后开始缓慢下降。结论 重庆市男女骨峰值年龄在25～29岁；中老年女性腰椎前后位L2-4Ward’s、Troch区骨密度变化早于股骨近端；男性骨密度在峰值年龄后逐渐均匀的下降。

Analysis of the bone mineral density in 1 320 healthy urban citizens in Chongqing

Objective To investigate the changes of bone mineral density(BMD) with age and the peak bone mass(PBM) in healthy urban citizens in Chongqing city for the diagnosis, prevention and treatment of primary osteoporosis. Methods The subjects, 1 320 healthy urban citizens living more than 10 years in Chongqing, were divided into 14 groups by every 5 years interval. BMD of lumbar spines(L 2-4 ), femoral neck(Neck), trochanter(Troch) and Ward's triangle(Ward's) were measured by dual energy X ray absorptiometry. Results The peak bone mass for all sites of the subjects appeared at the age of 25-29. In women, BMD decreased quickly during 45-55 years old in L 2-4 , Ward's and Troch as well as in Neck. In man, however, the bone loss increased gradually with aging. Conclusion PBM for each skeleton site appears during 25-29 years old.