参芪扶正注射液配合化疗治疗晚期肺癌的疗效观察

目的 比较参芪扶正注射液加化疗与单纯化疗治疗晚期肺癌患者疗效、毒副反应及生活质量的影响.方法 治疗组NP方案(诺维本 顺铂) 参芪液250 ml,化疗时使用,每天1次,连用6周,对照组单用NP方案.结果 连续2个周期化疗后,治疗组有效率46.7%,对照组36.7%,两组比较差异无显著性(P>0.05).治疗组病变进展率、血液毒副反应明显低于对照组,差异有显著性(P<0.05).生活质量评分治疗组高于对照组,两组间差异有显著性(P<0.05).结论 参芪扶正注射液与化疗联合治疗晚期肺癌可降低化疗对患者的毒副反应,改善患者的生活质量.

Efficacy of Shenqifuzheng Injection combined with chemotherapy in treating advanced lung cancer patients

Objective To compare the therapeutic effects, adverse reaction and quality of life when advanced lung cancer patients were treated with chemotherapy alone (control group) or combined with Shenqifuzheng Injection (a traditional Chinese Medicine injection, treated group). Methods In the treated group, beside NP scheme chemotherapy, a 250 ml of Shenqifuzheng Injection was given intravenously per day for 6 successive weeks, while to the control group, only chemotherapy was given. Results The effective rate in the treated group and the control group was 46.7% and 36.7% respectively after 2 cycles chemotherapy, with no significance was found. But the rate of progression, adverse reaction in blood were all lower in the treated group than in the control group(P<0.05), and the improvement in Karnofsky scores in the former was higher than in the latter (P<0.05). Conclusion Chemotherapy supplemented with Shenqifuzheng Injection shows apparent effect in treating advanced lung cancer, and it can lower the influence on adverse reaction of chemotherapy, and improve the quality of life of patients