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创伤后应激障碍患者静息状态下脑默认网络研究
引用本文:张晔,邱明国,谢兵,陈翰,张佳佳,张钰,张静娜,桑林琼,王莉,李敏,王健.创伤后应激障碍患者静息状态下脑默认网络研究[J].第三军医大学学报,2011,33(21):2271-2273.
作者姓名:张晔  邱明国  谢兵  陈翰  张佳佳  张钰  张静娜  桑林琼  王莉  李敏  王健
作者单位:1. 第三军医大学生物医学工程与医学影像学院医学信息与医学图像学教研室,重庆,400038
2. 第三军医大学西南医院放射科,重庆,400038
3. 第三军医大学西南医院康复科,重庆,400038
4. 第三军医大学护理学院心理学教研室,重庆,400038
基金项目:国家自然科学基金(30670595); 第三军医大学回国人员启动基金(2009XHG01); 重庆市自然科学基金(CSTC2009BB5019)~~
摘    要:目的 探讨创伤后应激障碍(post-traumatic stress disorders,PTSD)患者脑默认网络结构的变化.方法 采用静息态功能磁共振成像技术,采集9例临床确诊PTSD患者和10名正常自愿者静息态脑功能数据,并运用独立成分分析方法(ICA)分离出每例受试者的脑默认网络,将其结果进行组内分析和组间分析...

关 键 词:创伤后应激障碍  默认网络  功能磁共振成像  独立成分分析  静息状态

Brain's default network in patients with post-traumatic stress disorder at resting state
Zhang Ye,Qiu Mingguo,Xie Bing,Chen Han,Zhang Jiajia,Zhang Yu,Zhang Jingna,Sang Linqiong,Wang Li,Li Min,Wang Jian.Brain's default network in patients with post-traumatic stress disorder at resting state[J].Acta Academiae Medicinae Militaris Tertiae,2011,33(21):2271-2273.
Authors:Zhang Ye  Qiu Mingguo  Xie Bing  Chen Han  Zhang Jiajia  Zhang Yu  Zhang Jingna  Sang Linqiong  Wang Li  Li Min  Wang Jian
Institution:Zhang Ye1,Qiu Mingguo1,Xie Bing2,Chen Han3,Zhang Jiajia4,Zhang Yu4,Zhang Jingna1,Sang Linqiong1,Wang Li1,Li Min4,Wang Jian2(1Department of Medical Informatics and Medical Image,College of Biomedical Engineering and Medical Imaging,2Department of Radiology,Southwest Hospital,3Department of Rehabilitation,4Department of Psychology,School of Nursing Third Military Medical University,Chongqing,400038,China)
Abstract:Objective To explore the changes of brain's default network in patients with post-traumatic stress disorders(PTSD).Methods Resting-state functional magnetic resonance imaging(fMRI) was performed in 9 patients with PTSD and 10 healthy volunteers.Independent component analysis(ICA) was applied to separate the brain's default network of all the subjects.Two sample t-test was used to analyze the difference of the brain's default network between the patients and the healthy controls.Results A decreased functiona...
Keywords:post-traumatic stress disorder  default network  functional MRI  independent component analysis  resting-state  
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