| 白藜芦醇对呼吸道合胞病毒感染小鼠肺部病毒滴度及其气道炎症的影响 |
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| 引用本文： | 臧娜,谢晓虹,邓昱,李思敏,倪科,罗艳,王莉佳,刘恩梅.白藜芦醇对呼吸道合胞病毒感染小鼠肺部病毒滴度及其气道炎症的影响[J].第三军医大学学报,2011,0(18):1924-1927. |
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| 作者姓名： | 臧娜 谢晓虹 邓昱 李思敏 倪科 罗艳 王莉佳 刘恩梅 |
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| 作者单位： | 1. 重庆医科大学：儿童发育疾病研究省部共建教育部重点实验室,重庆,400014
2. 重庆医科大学：附属儿童医院呼吸一病房,重庆,400014 |
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| 基金项目： | 重庆医科大学校办重点课题项目(XBZD200808); 教育部新世纪优秀人才支持计划(NCET-06-0775); 重庆市第二批高等学校优秀人才支持计划~~ |
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| 摘 要： | 目的 研究白藜芦醇(resveratrol,RES)对呼吸道合胞病毒（respiratory syncytial virus，RSV）感染小鼠肺部病毒滴度及其所致气道炎症的影响。方法6～8周龄雌性BALB/c小鼠，环磷酰胺100 mg/kg腹腔注射后，随机分为对照组、RSV感染组、白藜芦醇腹腔注射组、白藜芦醇雾化组，每...
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| 关 键 词： | 白藜芦醇 RSV 气道炎症 气道高反应 |
Effect of resveratrol on pulmonary vurus titer and airway inflammation in mice infected with respiratory syncytial virus |
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| Zang Na,Xie Xiaohong,Deng Yu,Li Simin,Ni Ke,Luo Yan,Wang Lijia,Liu Enmei.Effect of resveratrol on pulmonary vurus titer and airway inflammation in mice infected with respiratory syncytial virus[J].Acta Academiae Medicinae Militaris Tertiae,2011,0(18):1924-1927. |
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| Authors: | Zang Na Xie Xiaohong Deng Yu Li Simin Ni Ke Luo Yan Wang Lijia Liu Enmei |
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| Institution: | Zang Na1,Xie Xiaohong2,Deng Yu2,Li Simin1,Ni Ke1,Luo Yan1,Wang Lijia1,Liu Enmei2(1Key Laboratory of Developmental Diseases in Childhood of Ministry of Education,2Department of Respiratory Medicine,Children's Hospital,Chongqing Medical University,Chongqing,400014,China) |
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| Abstract: | Objective To study the effect of resveratrol(RES) on pulmonary virus titer and airway inflammation in mice infected with respiratory syncytial virus(RSV).Methods Twenty-four female BALB/c mice at the age of 6-8 weeks,treated with intra-abdominal cyclophosphamide(CYP) at the dose of 100 mg/kg,were randomly divided into control group,RSV infection group,and RES treatment group(8 in each group).Five days after CYP treatment,a RES infection model was induced by intranasal drip of RES.One hour after RES infectio... |
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| Keywords: | resveratrol respiratory syncytial virus inflammation airway hyper-response |
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