血清PCT、CRP检测联合CT、X线对急性骨髓炎的诊断价值

目的探讨血清降钙素原(PCT)、C反应蛋白(CRP)检测联合CT、X线对急性骨髓炎的诊断价值。方法选取我院2015年1月~2019年1月期间收治的75例疑似急性骨髓炎患者为研究对象,比较急性骨髓炎患者与非急性骨髓炎患者血清中PCT、CRP水平,对比单独检测与联合检测的诊断结果。结果经过骨髓穿刺确诊急性骨髓炎48例,病变部位主要分布于股骨远端20例(41.67%)、胫骨近端15例(31.25%);急性骨髓炎患者血清中CRP、PCT水平高于对照组(P<0.05);受试者工作特征曲线(ROC)分析显示血清CRP、PCT、CT、X线联合检查与急性骨髓炎诊断相关的ROC曲线下方的面积大小(AUC)为0.90,高于CRP、PCT、CT、X线单独检测的0.58、0.63、0.64、0.70(P<0.05)。结论血清PCT、CRP检测联合CT、X线能有效提高急性骨髓炎的诊断价值。

Diagnostic Value of Serum PCT and CRP Detection Combined with CT and X-ray for Acute Osteomyelitis

Objective To investigate diagnostic value of serum procalcitonin(PCT)and C-reactive protein(CRP)combined with computed tomography(CT)and X-ray for acute osteomyelitis.Methods 75 patients with suspected acute osteomyelitis who were admitted to the hospital from January 2015 to January 2019 were enrolled.The PCT and CRP levels in serum of patients with acute osteomyelitis and non-acute osteomyelitis were compared.The diagnosis results of single detection and combination detection were compared.Results There were 48 cases with acute osteomyelitis confirmed by bone marrow aspiration.The lesions locations were mainly distributed in distal femur(20 cases,41.67%)and proximal tibia(15 cases,15.25%).The levels of CRP and PCT in serum of patients with acute osteomyelitis were higher than those in the control group(P<0.05).The receiver operating characteristic(ROC)curve analysis showed that area under the curve(AUC)of serum CRP,serum PCT,CT,X-ray combination examination for diagnosis of acute osteomyelitis was 0.90,which was higher than that of CRP,PCT,CT or X-ray alone(0.58,0.63,0.64 and 0.70)(P<0.05).Conclusion Serum PCT and CRP combined with CT and X-ray can effectively improve diagnostic value for acute osteomyelitis.