第二代双源CT双能量心肌灌注成像与SPECT心肌灌注的对照研究

目的对比SPECT,探讨双源CT(DSCT)双能量心肌灌注成像的临床应用价值。方法搜集18例临床怀疑冠心痛或已知冠心病史的患者行双源CT双能量心肌灌注成像和静息/负荷心肌灌注锝-99mSPECT显像检查,并对其影像表现进行分析。结果 DSCT双能量心肌灌注成像检查1 8例患者,发现阳性1 4例,阴性4例。对比SPECT检查,14例DSCT阳性病例中,SPECT均发现了相同心肌部位的灌注缺损。而4例阴性病例中,SPECT检查有1例有心肌缺血。二者检出心肌灌注缺损的差异性无统计学意义(P0.05)。结论DSCT双能量心肌灌注成像发现心肌灌注缺损的能力与SPECT大致相符,对冠心病的诊断有较大价值。

The Comparison of the Second Generation Dual-source Dual-energy CT Myocardial Perfusion Imaging in Patients and Myocardial Perfusion Imaging by SPECT

Objective To evaluate the clinical value of the myocardial perfusion imaging dual-source CT (DSCT) dual energy, in the comparison of SPECT.Methods 18 cases of clinically suspected or known coronary artery disease were of collected. Then the patients underwent the myocardial perfusion imaging of DSCT and resting /loaded technetium-99m SPECT.The imaging findings then were analyzed further.Results In 18 patients with DSCT dual energy myocardial perfusion imaging, 14 cases were positive, when 4 cases were negative. Compared with SPECT examination, the same cardiac perfusion defect of 14 positive cases were found in SPECT as in DSCT. Among 4 negative cases of DSCT examination, loaded SPECT detected myocardial ischemia in 1 case. Detection rates of cardiac perfusion defect between DSCT with SPECT showed no significant difference(P>0.05).Conclusion The myocardial perfusion imaging in DSCT dual energy possess the similar capability in myocardial perfusion defects with SPECT, and manifest great diagnosis value for coronary heart disease.