| YMB注射液对大鼠血液流变学的影响 |
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| 引用本文： | 杨华蓉 李幼平. YMB注射液对大鼠血液流变学的影响[J]. 华西医科大学学报, 2000, 31(2): 230-232 |
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| 作者姓名： | 杨华蓉 李幼平 |
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| 作者单位： | [1]华西医科大学基础医学院药理学教研室 [2]附属第一医院移植免疫实验室 |
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| 摘 要： | 为研究ＹＭＢ注射液抗移植物慢性失功（ｃｈｒｏｎｉｃ ａｌｌｏｇｒａｆｔ ｄｙｓｆｕｎｃｔｉｏｎ，ＣＡＤ）的作用机理，作者选取传统活因化阏中药复方丹参注射液（ＦＤＩ）为阳性对照，以生理盐水为阴性对照，考察中药ＹＭＢ注射液对正常大鼠及血瘀模型大鼠血液流变学参数的影响。结果显示，中药ＹＭＢ注射液对因液流变学参数无影响，但能有效降低血瘀模型大鼠的全血粘度和还原全血粘度。提示ＹＭＢ注射液可能通过活血化瘀、降
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| 关 键 词： | YMB注射液 急性血瘀 血液流变学 大鼠 CAD |
Effects of YMB injection on hemorheology in rats] |
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| H Yang,J Chen,S Cai,Y Li,Q Tang,Y Liu. Effects of YMB injection on hemorheology in rats][J]. Journal of West China University of Medical Sciences, 2000, 31(2): 230-232 |
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| Authors: | H Yang J Chen S Cai Y Li Q Tang Y Liu |
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| Affiliation: | Department of Pharmacology, School of Basic Medical Sciences, WCUMS, Chengdu 610041. |
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| Abstract: | This study was designed to elucidate the mechanism of YMB Injection on anti-CAD therapy. Fufang Danshen Injection was used as positive control and saline was taken as negative control to study the effects of traditional medicine YMB Injection on hemorheological parameters in normal rats and hypostasis rats. The results showed YMB Injection had no effect on hemorheological parameters of normal rats, but it could effectively decrease whole blood viscosity and whole blood reduction viscosity of hypostasis rats. The data implied that YMB Injection could decrease blood viscosity and hence improve blood supply of the graft in anti-CAD therapy. |
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