首页 | 本学科首页   官方微博 | 高级检索  
检索        

马桑内酯点燃大鼠海马脑片CA1区的双脉冲...
引用本文:郭亮,柴慧霞.马桑内酯点燃大鼠海马脑片CA1区的双脉冲...[J].华西医科大学学报,1992,23(4):399-402.
作者姓名:郭亮  柴慧霞
摘    要:

关 键 词:癫痫  马桑内酯  海马  氨基丁酸

Observation of paired-pulse depression in CA1 region of hippocampal slices from coriaria lactone-kindled rats]
L Guo,H Chai,Y Xie,X Liu.Observation of paired-pulse depression in CA1 region of hippocampal slices from coriaria lactone-kindled rats][J].Journal of West China University of Medical Sciences,1992,23(4):399-402.
Authors:L Guo  H Chai  Y Xie  X Liu
Abstract:Paired-pulse depression (PPD) technique was used to investigate the potency of recurrent synaptic inhibition mediated by GABA in area CA1 of 54 hippocampal slices from coriaria lactone (CL)-kindled and control rats. When paired stimuli were sent to the axon of CA1 pyramidal cell and Schaffer collaterals, the effect of population spike PPD lasted about 40-60ms; no significant change was observed on PPD potency between kindled and control groups (P = 0.06, 2-way ANOVA). The results indicate that the GABA-ergic synaptic inhibition seemed not to play a key role in the maintenance of the chemical kindling induced by CL.
Keywords:
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号