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α干扰素对狼疮性肾炎红细胞C_3b受体活性的影响
引用本文:娄探奇,尹培达,唐世聪.α干扰素对狼疮性肾炎红细胞C_3b受体活性的影响[J].中山大学学报(医学科学版),1993(2).
作者姓名:娄探奇  尹培达  唐世聪
作者单位:中山医科大学附属第一医院肾内科,中山医科大学附属第一医院肾内科,中山医科大学附属第一医院肾内科 临床博士研究生 本校附属第三医院肾内
摘    要:干扰素系一种免疫调节因子,是否对红细胞免疫功能产生影响,目前研究尚少。作者观察了20例狼疮性肾炎红细胞C_3b受体在体外对干扰素刺激的反应。结果发现,a干扰素能显著增强红细胞C_3b受体活性,其激活效应与适合的干扰素剂量及激活时间有关。结果提示,干扰素可能参与红细胞免疫的调节,为临床上治疗红细胞免疫缺陷提供了一条新的研究途径.

关 键 词:干扰素  红细胞C_3b受体  狼疮性肾炎

ENHANCEMENT OF ERYTHROCYTE C3b RECEPTOR ACTIVITY OF LUPUS NEPHRITIS BY INTERFERON ALFA
Lou Tanqi Yin Peida Tang Shicong.ENHANCEMENT OF ERYTHROCYTE C3b RECEPTOR ACTIVITY OF LUPUS NEPHRITIS BY INTERFERON ALFA[J].Journal of Sun Yatsen University(Medical Sciences),1993(2).
Authors:Lou Tanqi Yin Peida Tang Shicong
Abstract:Interferon (IFN) is a regulating factor of immune system. The enhancing effect on erythrocyte C3b receptor by IFN was investigated in vitro. The results showed that IFN alfa, in vitro, enhanced the activity of erythrocyte C3b receptor markedly in 20 patients with lupus nephritis. This effect was correlated with the dose of IFN alfa and the time acting on erythrocyte C3b receptor. These results indicated that IFN may take part in regulation of red cell immune and can be used to treat patients with lupus nephritis to improve the red cell immune function.
Keywords:interferon  erythrocyte C3b receptor  lupus nephritis
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